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Small Bowel Malignancies in Patients Undergoing Capsule Endoscopy for Iron Deficiency Anemia
 
 
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Diagnostics
Volume 12
Issue 1
10.3390/diagnostics12010149
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Review
Peer-Review Record

Review: Colon Capsule Endoscopy in Inflammatory Bowel Disease

Diagnostics 2022, 12(1), 149; https://doi.org/10.3390/diagnostics12010149
by Writaja Halder 1, Faidon-Marios Laskaratos 2,*, Hanan El-Mileik 1, Sergio Coda 1, Stevan Fox 1, Saswata Banerjee 1 and Owen Epstein 3
Reviewer 1: Anonymous
Reviewer 2: Anonymous
Diagnostics 2022, 12(1), 149; https://doi.org/10.3390/diagnostics12010149
Submission received: 1 December 2021 / Revised: 25 December 2021 / Accepted: 4 January 2022 / Published: 8 January 2022
(This article belongs to the Special Issue Capsule Endoscopy: Clinical Impacts and Innovation since 2001)

Round 1

Reviewer 1 Report

Very well written review article.

Colon capsule endoscopy is yet to take off in a big way for IBD due to all the limitations described by authors, biggest one being inability to obtain histological evidence of diagnosis, disease activity or remission, especially when colonoscopy can provide these, especially in most  IBD patients other than those with involvement of small bowel proximal to terminal ileum( that cannot be reached with conventional ileocolonoscopy)

The most important utility of capsule endoscopy remains in suspected IBD in my opinion where bidirectional endoscopy +/- small bowel imaging(MRE or CTE) have not quite helped confirm the diagnosis of IBD in patients with symptoms and or suggestive associations( like iron deficiency anemia, malabsorptive picture etc)

I think if cost effectiveness comparison of colon capsule versus colonoscopy could be included in this review, it would add to the value of the paper.This is all the more important for healthcare systems like the US, where insurance companies can be difficult to get past for getting such procedures approved for these indications.

Author Response

Please see cover letter with responses to reviewers

Author Response File: Author Response.pdf

Reviewer 2 Report

This is an important review on the role of CCE in patients with suspected or confirmed IBD. It is well-presented and presents useful information. I have minor comment. It would be better to show examples of endoscopic images by CCE and/or PCE in IBD patients.  

Author Response

Please see cover letter with responses to reviewers

Author Response File: Author Response.pdf

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