Efficacy and Safety of Non-Anesthesiologist Administration of Propofol Sedation in Endoscopic Ultrasound: A Propensity Score Analysis
Abstract
:1. Introduction
2. Materials and Methods
2.1. Patients
2.2. Sedation
2.3. Outcomes
2.4. Statistical Analysis
3. Results
3.1. Patients
3.2. Safety and Efficacy
4. Discussion
5. Conclusions
Author Contributions
Funding
Conflicts of Interest
References
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Variable | NAAP (n = 395) | Controls (n = 437) | p Value |
---|---|---|---|
Age (years) | 68 ± 9 | 65 ± 7 | 0.54 |
Gender: Male | 229 (57.9%) | 279 (63.8%) | 0.08 |
Female | 166 (42.1%) | 158(36.2%) | |
Comorbidities | 128 (32.4%) | 143 (32.7%) | 0.77 |
ASA score ≤II | 304 (76.9%) | 361 (82.6%) | 0.05 |
EUS-FNA/FNB | 315 (79.7%) | 345 (78.9%) | 0.77 |
Other EUS procedures | 80 (20.3%) | 92 (21.1%) | |
Number of previous endoscopies | 1.3 ± 1.2 | 2.1 ± 1.5 | 0.65 |
Location: Pancreas | 305 (77.2%) | 352 (80.5%) | 0.26 |
Other | 90 (22.8%) | 85 (19.5%) |
Variable | NAAP (n = 305) | Controls (n = 305) | p Value |
---|---|---|---|
Age (years) | 67 ± 3 | 66 ± 9 | 0.91 |
Gender: Male | 183 (60%) | 183 (60%) | 1.0 |
Female | 122 (40%) | 122 (40%) | |
Comorbidities | 97 (31.8%) | 97 (31.8%) | 1.0 |
ASA score ≤2 | 252 (82.6%) | 250 (81.9%) | 0.89 |
EUS-FNA/FNB | 248 (81.3%) | 250 (81.9%) | 0.93 |
Other EUS procedures | 57 (18.7%) | 55 (18.1%) | |
Number of previous endoscopies | 1.2 ± 1 | 1.3 ± 1.3 | 0.85 |
Location: Pancreas | 250 (81.9%) | 248 (81.3%) | 0.93 |
Other | 55 (18.1%) | 57 (18.7%) |
NAAP (305 Patients) | Controls (305 Patients) | p-Value a | |
---|---|---|---|
Safety | |||
• Any major complications * | 1 (0.3%) | 1 (0.3%) | 1.0 |
• Any minor complications + | 13 (4.2%) | 10 (3.2%) | 0.52 |
• Mean propofol dose (mg) | 85.4 ± 25.5 | 92.4 ± 30.5 | 0.24 |
Efficacy | |||
• Patient satisfaction with the procedure § | 8.5 ± 1.5 | 8.3 ± 1.5 | 0.88 |
• Endoscopist satisfaction with the procedure § | 8.3 ± 2 | 8.2 ± 1.8 | 0.75 |
• Quality of EUS § | 9 ± 1 | 9 ± 0.8 | 1.0 |
• Overall pain during the procedure § | 2.3 ± 1 | 1.8 ± 1 | 0.67 |
• Pain or discomfort upon awakening § | 1 ± 0.5 | 1 ± 0.5 | 0.72 |
• Mean procedure duration (min) | 20 ± 23 | 23 ± 18 | 0.62 |
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Facciorusso, A.; Turco, A.; Barnabà, C.; Longo, G.; Dipasquale, G.; Muscatiello, N. Efficacy and Safety of Non-Anesthesiologist Administration of Propofol Sedation in Endoscopic Ultrasound: A Propensity Score Analysis. Diagnostics 2020, 10, 791. https://doi.org/10.3390/diagnostics10100791
Facciorusso A, Turco A, Barnabà C, Longo G, Dipasquale G, Muscatiello N. Efficacy and Safety of Non-Anesthesiologist Administration of Propofol Sedation in Endoscopic Ultrasound: A Propensity Score Analysis. Diagnostics. 2020; 10(10):791. https://doi.org/10.3390/diagnostics10100791
Chicago/Turabian StyleFacciorusso, Antonio, Antonio Turco, Carlo Barnabà, Grazia Longo, Graziano Dipasquale, and Nicola Muscatiello. 2020. "Efficacy and Safety of Non-Anesthesiologist Administration of Propofol Sedation in Endoscopic Ultrasound: A Propensity Score Analysis" Diagnostics 10, no. 10: 791. https://doi.org/10.3390/diagnostics10100791
APA StyleFacciorusso, A., Turco, A., Barnabà, C., Longo, G., Dipasquale, G., & Muscatiello, N. (2020). Efficacy and Safety of Non-Anesthesiologist Administration of Propofol Sedation in Endoscopic Ultrasound: A Propensity Score Analysis. Diagnostics, 10(10), 791. https://doi.org/10.3390/diagnostics10100791