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Blue Light in Dermatology

Department of Dermatology, Pediatric Dermatology and Dermatological Oncology, Medical University of Łódź, 90-419 Łódź, Poland
Author to whom correspondence should be addressed.
Academic Editor: Enzo Berardesca
Life 2021, 11(7), 670;
Received: 16 June 2021 / Revised: 2 July 2021 / Accepted: 6 July 2021 / Published: 8 July 2021
(This article belongs to the Special Issue Frontiers of Dermatological Research)
Phototherapy is an important method of dermatological treatments. Ultraviolet (280–400 nm) therapy is of great importance; however, there are concerns of its long-term use, as it can lead to skin aging and carcinogenesis. This review aims to evaluate the role and the mechanism of action of blue light (400–500 nm), a UV-free method. The main mediators of cellular responses to blue light are nitric oxide (NO) and reactive oxygen species (ROS). However, the detailed mechanism is still not fully understood. It was demonstrated that blue light induces an anti-inflammatory and antiproliferative effect; thus, it may be beneficial for hyperproliferative and chronic inflammatory skin diseases such as atopic dermatitis, eczema, and psoriasis. It was also found that blue light might cause the reduction of itching. It may be beneficial on hair growth and may be used in the treatment of acne vulgaris by reducing follicular colonization of Propionibacterium acnes. Further studies are needed to develop accurate protocols, as the clinical effects depend on the light parameters as well as the treatment length. There are no major adverse effects observed yet, but long-term safety should be monitored as there are no studies considering the long-term effects of blue light on the skin. View Full-Text
Keywords: blue light; phototherapy; dermatology blue light; phototherapy; dermatology
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MDPI and ACS Style

Sadowska, M.; Narbutt, J.; Lesiak, A. Blue Light in Dermatology. Life 2021, 11, 670.

AMA Style

Sadowska M, Narbutt J, Lesiak A. Blue Light in Dermatology. Life. 2021; 11(7):670.

Chicago/Turabian Style

Sadowska, Magdalena, Joanna Narbutt, and Aleksandra Lesiak. 2021. "Blue Light in Dermatology" Life 11, no. 7: 670.

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