Next Article in Journal
A Study on Interaction of Gaze Pointer-Based User Interface in Mobile Virtual Reality Environment
Next Article in Special Issue
Chiral Analysis of Pesticides and Drugs of Environmental Concern: Biodegradation and Enantiomeric Fraction
Previous Article in Journal
On the Form and Growth of Complex Crystals: The Case of Tsai-Type Clusters
Previous Article in Special Issue
Enantiomeric Separation of Tramadol and Its Metabolites: Method Validation and Application to Environmental Samples
Open AccessFeature PaperReview

Chiral Stationary Phases for Liquid Chromatography Based on Chitin- and Chitosan-Derived Marine Polysaccharides

1
Laboratório de Química Orgânica e Farmacêutica, Departamento de Ciências Químicas, Faculdade de Farmácia, Rua de Jorge Viterbo Ferreira 228, 4050-313 Porto, Portugal
2
Interdisciplinary Centre of Marine and Environmental Research (CIIMAR), Edifício do Terminal de Cruzeiros do Porto de Leixões, Av. General Norton de Matos s/n, 4050-208 Matosinhos, Portugal
3
CESPU, Instituto de Investigação e Formação Avançada em Ciências e Tecnologias da Saúde (IINFACTS), Rua Central de Gandra, 1317, 4585-116 Gandra PRD, Portugal
*
Author to whom correspondence should be addressed.
Symmetry 2017, 9(9), 190; https://doi.org/10.3390/sym9090190
Received: 1 August 2017 / Revised: 6 September 2017 / Accepted: 6 September 2017 / Published: 11 September 2017
(This article belongs to the Special Issue Chiral Separations)
The development of chiral stationary phases (CSPs) for liquid chromatography (LC) revolutionized the enantioseparation and, nowadays, different types of CSPs are commercially available. Polysaccharide-based CSPs are one of the most versatile and widely used for both analytical and preparative applications and they are able to resolve several classes of racemates. Phenylcarbamates of amylose and cellulose derivatives are the most successful; however, polysaccharide-based CSPs comprising marine-derived polysaccharides are also described revealing high chiral recognition abilities and wider range of mobile phases. A literature survey covering the report on chitin and chitosan based CSPs is presented. The chemical structure of the chiral selectors, their development and applications in chiral LC are emphasized. View Full-Text
Keywords: liquid chromatography; chiral stationary phases; marine polysaccharides; chitin; chitosan liquid chromatography; chiral stationary phases; marine polysaccharides; chitin; chitosan
Show Figures

Figure 1

MDPI and ACS Style

Ribeiro, J.; Tiritan, M.E.; Pinto, M.M.; Fernandes, C. Chiral Stationary Phases for Liquid Chromatography Based on Chitin- and Chitosan-Derived Marine Polysaccharides. Symmetry 2017, 9, 190.

Show more citation formats Show less citations formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop