Studies on the presence of pharmaceuticals in water were carried out on the riverbank filtration site, Krajkowo–Poznań (Poland). A preliminary investigation conducted in 3 sampling points showed the presence of pharmaceuticals in both surface water and bank filtrate. Based on the above, an extended analysis was made in July, August and October 2018 and included surface water and wells located at a different distance (5–250 m) and travel time (1–150 days) from source water (Warta River). Firstly, 75 compounds (antibiotics, anti-inflammatory and analgesic drugs, psychotropic drugs, x-ray agents and β-blockers) were tested and 25 of them were detected in the river or bank filtrate. The highest concentrations were observed in source water and then were reduced along the flow path. The sampling points located close to the river (<38 m) are characterized by low removal. Higher removal is visible in wells located 64–82 m away from the river, while 250 m from the river most compounds are completely attenuated. Carbamazepine, gabapentin, tramadol, oxypurinol, fluconazole, and lamotrigine are the most common compounds. Some of the tested parameters occur only in the river water, e.g., iopromide, diclofenac, iohexol, clindamycin, fexofenadine and valsartan. The research shows that at the site, a significant attenuation of pharmaceuticals can be achieved at travel times of 40–50 days and distances of 60–80 m, although higher values are ensured when the well is located more than 250 m away.
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