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WNT Signaling in Disease

Division of Science, Yale-NUS College, Yale-NUS College Research Labs @ E6, E6, 5 Engineering Drive 1, #04-02, Singapore 117608, Singapore
Author to whom correspondence should be addressed.
These authors contributed equally to the paper.
Cells 2019, 8(8), 826;
Received: 8 July 2019 / Revised: 1 August 2019 / Accepted: 2 August 2019 / Published: 3 August 2019
(This article belongs to the Special Issue Wnt Signaling in Health and Diseases)
PDF [1914 KB, uploaded 14 August 2019]
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Developmental signaling pathways control a vast array of biological processes during embryogenesis and in adult life. The WNT pathway was discovered simultaneously in cancer and development. Recent advances have expanded the role of WNT to a wide range of pathologies in humans. Here, we discuss the WNT pathway and its role in human disease and some of the advances in WNT-related treatments. View Full-Text
Keywords: WNT; cancer; metabolic syndrome; Alzheimer’s disease WNT; cancer; metabolic syndrome; Alzheimer’s disease

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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

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Ng, L.F.; Kaur, P.; Bunnag, N.; Suresh, J.; Sung, I.C.H.; Tan, Q.H.; Gruber, J.; Tolwinski, N.S. WNT Signaling in Disease. Cells 2019, 8, 826.

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