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WNT Signaling in Disease

Division of Science, Yale-NUS College, Yale-NUS College Research Labs @ E6, E6, 5 Engineering Drive 1, #04-02, Singapore 117608, Singapore
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These authors contributed equally to the paper.
Cells 2019, 8(8), 826; https://doi.org/10.3390/cells8080826
Received: 8 July 2019 / Revised: 1 August 2019 / Accepted: 2 August 2019 / Published: 3 August 2019
(This article belongs to the Special Issue Wnt Signaling in Health and Diseases)
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Abstract

Developmental signaling pathways control a vast array of biological processes during embryogenesis and in adult life. The WNT pathway was discovered simultaneously in cancer and development. Recent advances have expanded the role of WNT to a wide range of pathologies in humans. Here, we discuss the WNT pathway and its role in human disease and some of the advances in WNT-related treatments. View Full-Text
Keywords: WNT; cancer; metabolic syndrome; Alzheimer’s disease WNT; cancer; metabolic syndrome; Alzheimer’s disease
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Ng, L.F.; Kaur, P.; Bunnag, N.; Suresh, J.; Sung, I.C.H.; Tan, Q.H.; Gruber, J.; Tolwinski, N.S. WNT Signaling in Disease. Cells 2019, 8, 826.

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