Genetic Association between Swine Leukocyte antigen Class II Haplotypes and Reproduction Traits in Microminipigs
Abstract
:1. Introduction
2. Materials and Methods
2.1. Animals
2.2. SLA Class II Typing
2.3. Measurement of Reproductive Performances
2.4. Statistical Analyses
3. Results
3.1. Reproductive Performance in MMPs
3.2. Association between SLA Class II Haplotypes and Fertility Index
3.3. Association of SLA Class II Haplotypes and Gestation Periods
3.4. Association between SLA Class II Haplotypes and Litter Sizes at Birth and Weaning
3.5. Association of SLA Class II Haplotypes and Number of Stillbirths per Delivery
4. Discussion
5. Conclusions
Author Contributions
Acknowledgments
Conflicts of Interest
References
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SLA Class II | Allele Specificity by Low Resolution Typing | * Expected Allele Specificity by High Resolution Typing | Number of Haplotypes (Frequency (%)) | |||||
---|---|---|---|---|---|---|---|---|
haplotype | DRB1 | DQB1 | DRB1 | DQB1 | Dams | Sires | ||
Lr-0.7 | 06:XX | 06:XX | 06:01 | 06:01 | 2 | (0.8) | 1 | (0.9) |
Lr-0.11 | 09:XX | 04:XX | 09:01 | 04:01:02/04:02 | 19 | (7.4) | 10 | (8.6) |
Lr-0.13 | 04:XX | 03:XX | 04:03 | 03:03 | 13 | (5.0) | 2 | (1.7) |
Lr-0.16 | 11:XX | 06:XX | 11:03 | 06:01 | 16 | (6.2) | 7 | (6.0) |
Lr-0.17 | 08:XX | 05:XX | 08:01 | 05:01/05:02 | 44 | (17.1) | 18 | (15.5) |
Lr-0.18 | 14:XX | 04:XX | 14:01 | 04:01:02/04:02 | 24 | (9.3) | 8 | (6.9) |
Lr-0.23 | 10:XX | 06:XX | 10:01 | 06:01 | 79 | (30.6) | 42 | (36.2) |
Lr-0.37 | 07:XX | 05:XX | 07:01 | 05:01/05:02 | 61 | (23.6) | 28 | (24.1) |
Trait | Mean * | SE * | Number of Haplotypes ** |
---|---|---|---|
Gestation period (day) | 115.1 | 0.06 | 2760 |
Litter size at birth (No. of piglets) | 5.48 | 0.04 | 2804 |
Litter size at weaning (No. of piglets) | 3.88 | 0.04 | 2804 |
No. of stillbirth/delivery (No. of piglets) | 0.97 | 0.03 | 2768 |
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Ando, A.; Imaeda, N.; Matsubara, T.; Takasu, M.; Miyamoto, A.; Oshima, S.; Nishii, N.; Kametani, Y.; Shiina, T.; Kulski, J.K.; et al. Genetic Association between Swine Leukocyte antigen Class II Haplotypes and Reproduction Traits in Microminipigs. Cells 2019, 8, 783. https://doi.org/10.3390/cells8080783
Ando A, Imaeda N, Matsubara T, Takasu M, Miyamoto A, Oshima S, Nishii N, Kametani Y, Shiina T, Kulski JK, et al. Genetic Association between Swine Leukocyte antigen Class II Haplotypes and Reproduction Traits in Microminipigs. Cells. 2019; 8(8):783. https://doi.org/10.3390/cells8080783
Chicago/Turabian StyleAndo, Asako, Noriaki Imaeda, Tatsuya Matsubara, Masaki Takasu, Asuka Miyamoto, Shino Oshima, Naohito Nishii, Yoshie Kametani, Takashi Shiina, Jerzy K. Kulski, and et al. 2019. "Genetic Association between Swine Leukocyte antigen Class II Haplotypes and Reproduction Traits in Microminipigs" Cells 8, no. 8: 783. https://doi.org/10.3390/cells8080783