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Data Descriptor

GEDS: A Gene Expression Display Server for mRNAs, miRNAs and Proteins

Department of Bioinformatics and Systems Biology, Hubei Bioinformatics and Molecular Imaging Key Laboratory, Key Laboratory of Molecular Biophysics of the Ministry of Education, College of Life Science and Technology, Huazhong University of Science and Technology, Hubei, Wuhan 430074, China
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Author to whom correspondence should be addressed.
These authors contribute equally to work.
Cells 2019, 8(7), 675; https://doi.org/10.3390/cells8070675
Received: 5 June 2019 / Revised: 2 July 2019 / Accepted: 3 July 2019 / Published: 3 July 2019
(This article belongs to the Special Issue microRNA Bioinformatics)
High-throughput technologies generate a tremendous amount of expression data on mRNA, miRNA and protein levels. Mining and visualizing the large amount of expression data requires sophisticated computational skills. An easy to use and user-friendly web-server for the visualization of gene expression profiles could greatly facilitate data exploration and hypothesis generation for biologists. Here, we curated and normalized the gene expression data on mRNA, miRNA and protein levels in 23,315, 9009 and 9244 samples, respectively, from 40 tissues (The Cancer Genome Atlas (TCGA) and Genotype-Tissue Expression (GETx)) and 1594 cell lines (Cancer Cell Line Encyclopedia (CCLE) and MD Anderson Cell Lines Project (MCLP)). Then, we constructed the Gene Expression Display Server (GEDS), a web-based tool for quantification, comparison and visualization of gene expression data. GEDS integrates multiscale expression data and provides multiple types of figures and tables to satisfy several kinds of user requirements. The comprehensive expression profiles plotted in the one-stop GEDS platform greatly facilitate experimental biologists utilizing big data for better experimental design and analysis. GEDS is freely available online. View Full-Text
Keywords: miRNA; mRNA; protein; gene expression; visualization miRNA; mRNA; protein; gene expression; visualization
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MDPI and ACS Style

Xia, M.; Liu, C.-J.; Zhang, Q.; Guo, A.-Y. GEDS: A Gene Expression Display Server for mRNAs, miRNAs and Proteins. Cells 2019, 8, 675. https://doi.org/10.3390/cells8070675

AMA Style

Xia M, Liu C-J, Zhang Q, Guo A-Y. GEDS: A Gene Expression Display Server for mRNAs, miRNAs and Proteins. Cells. 2019; 8(7):675. https://doi.org/10.3390/cells8070675

Chicago/Turabian Style

Xia, Mengxuan, Chun-Jie Liu, Qiong Zhang, and An-Yuan Guo. 2019. "GEDS: A Gene Expression Display Server for mRNAs, miRNAs and Proteins" Cells 8, no. 7: 675. https://doi.org/10.3390/cells8070675

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