Next Article in Journal
Inosine Triphosphate Pyrophosphatase (ITPase): Functions, Mutations, Polymorphisms and Its Impact on Cancer Therapies
Next Article in Special Issue
Analysis of the Glucose-Dependent Transcriptome in Murine Hypothalamic Cells
Previous Article in Journal
The Influence of Gut Microbiota on Neurogenesis: Evidence and Hopes
Previous Article in Special Issue
LEAP-2 Counteracts Ghrelin-Induced Food Intake in a Nutrient, Growth Hormone and Age Independent Manner
 
 
Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
Journals
Cells
Volume 11
Issue 3
10.3390/cells11030383
Review Report
cells-logo
Submit to this Journal Review for this Journal Propose a Special Issue
► Article Menu

Article Menu

share Share announcement Help format_quote Cite question_answer Discuss in SciProfiles
Review
Peer-Review Record

Physiological Function during Exercise and Environmental Stress in Humans—An Integrative View of Body Systems and Homeostasis

Cells 2022, 11(3), 383; https://doi.org/10.3390/cells11030383
by Gavin Travers 1, Pascale Kippelen 2,3, Steven J. Trangmar 4 and José González-Alonso 2,3,*
Reviewer 1: Anonymous
Reviewer 2: Anonymous
Reviewer 3: Anonymous
Cells 2022, 11(3), 383; https://doi.org/10.3390/cells11030383
Submission received: 29 December 2021 / Revised: 18 January 2022 / Accepted: 19 January 2022 / Published: 24 January 2022
(This article belongs to the Collection Brain-Body Interactions in the Maintenance of Homeostasis: An Honorary Issue in Memory of Prof. Claude Bernard)

Round 1

Reviewer 1 Report

Of the manuscript "Physiological function during exercise and environmental stress in humans - an integrative view of body systems and homeostasis" I report the following:

The manuscript is very well written and addresses the issue raised with excellence. But I have two comments: the text is very long, it presents in some parts a detailed description of each topic, with long sentences that could be shortened. Besides, at the beginning of each organ / system analyzed, a description of its functions is made, perhaps unnecessary, and more suitable for readers who are approaching the physiology of the systems.

A second comment refers to the "control mechanisms" of the homeostatic phenomenon. Here the review is extensive the nervous system, but it is more focused on blood flow and brain metabolism, although in the seventh point (“Organ systems interactions - future research directions”) it addresses some neural control mechanisms itself, Also, it partly touches on autonomic regulation in the cardiovascular chapter but no comment or description is made about the role of hormones as controllers of the internal environment, I believe that a paragraph on this should be incorporated that could be in the mentioned seventh point.

Author Response

Please find our response to all reviewer comments attached.

Author Response File: Author Response.pdf

Reviewer 2 Report

This review is interesting and useful since it examines the body function and the dynamic homeostasis during exercise and environmental stress, from several perspectives. However, nothing is mentioned about the inducible factor of hypoxia as a possible mechanism that would regulate the oxygen demand by the tissues, I think this issue is also relevant. 

Author Response

Please find our responses to all reviewer comments in the file attached.

Author Response File: Author Response.pdf

Reviewer 3 Report

This Review is good and focus interesting.

Author Response

We thank the reviewer for their kind words regarding the manuscript. We hope this will be a valuable teaching resource as well as facilitate future research in integrative physiology.

Back to TopTop