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Polymers
Volume 15
Issue 2
10.3390/polym15020271
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Article

Porous Scaffolds Based on Polydopamine/Chondroitin Sulfate/Polyvinyl Alcohol Composite Hydrogels

by
Zuwu Tang
1,
Meiqiong Yu
1,2,
Ajoy Kanti Mondal
3 and
Xinxing Lin
1,*
1
School of Materials and Environmental Engineering, Fujian Polytechnic Normal University, No.1, Campus New Village, Longjiang Street, Fuzhou 350300, China
2
College of Material Engineering, Fujian Agriculture and Forestry University, Fuzhou 350108, China
3
Leather Research Institute, Bangladesh Council of Scientific and Industrial Research, Dhaka 1350, Bangladesh
*
Author to whom correspondence should be addressed.
Polymers 2023, 15(2), 271; https://doi.org/10.3390/polym15020271
Submission received: 24 November 2022 / Revised: 22 December 2022 / Accepted: 27 December 2022 / Published: 5 January 2023
(This article belongs to the Special Issue Advanced Polymer-Based Composites for Biomedical Applications)
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Abstract

In this paper, porous scaffolds based on composite hydrogels were fabricated using polydopamine (PDA), chondroitin sulfate (CS), and polyvinyl alcohol (PVA) via the freezing/thawing method. Different characteristics of the prepared composite hydrogels, including the pore sizes, compression strength, lap shear strength, mass loss, and cytocompatibility were investigated. Scanning electron microscope images (SEM) displayed the hydrogel pore sizes, ranging from 20 to 100 μm. The composite hydrogel exhibited excellent porosity of 95.1%, compression strength of 5.2 MPa, lap shear strength of 21 kPa on porcine skin, and mass loss of 16.0%. In addition, the composite hydrogel possessed good relative cell activity of 97%. The PDA/CS/PVA hydrogel is cytocompatible as a starting point, and it can be further investigated in tissue engineering.
Keywords: composite hydrogel; cytocompatibility; porosity; porous scaffolds composite hydrogel; cytocompatibility; porosity; porous scaffolds

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MDPI and ACS Style

Tang, Z.; Yu, M.; Mondal, A.K.; Lin, X. Porous Scaffolds Based on Polydopamine/Chondroitin Sulfate/Polyvinyl Alcohol Composite Hydrogels. Polymers 2023, 15, 271. https://doi.org/10.3390/polym15020271

AMA Style

Tang Z, Yu M, Mondal AK, Lin X. Porous Scaffolds Based on Polydopamine/Chondroitin Sulfate/Polyvinyl Alcohol Composite Hydrogels. Polymers. 2023; 15(2):271. https://doi.org/10.3390/polym15020271

Chicago/Turabian Style

Tang, Zuwu, Meiqiong Yu, Ajoy Kanti Mondal, and Xinxing Lin. 2023. "Porous Scaffolds Based on Polydopamine/Chondroitin Sulfate/Polyvinyl Alcohol Composite Hydrogels" Polymers 15, no. 2: 271. https://doi.org/10.3390/polym15020271

APA Style

Tang, Z., Yu, M., Mondal, A. K., & Lin, X. (2023). Porous Scaffolds Based on Polydopamine/Chondroitin Sulfate/Polyvinyl Alcohol Composite Hydrogels. Polymers, 15(2), 271. https://doi.org/10.3390/polym15020271

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