Yerba Mate Extract in Microfibrillated Cellulose and Corn Starch Films as a Potential Wound Healing Bandage
Abstract
:1. Introduction
2. Materials and Methods
2.1. Materials
2.2. Film Formation
2.2.1. Yerba Mate Collection and Extract
2.2.2. Starch Solution
2.2.3. Microfibrillated Cellulose Gel
2.2.4. Solvent Evaporation Casting Film Formation
2.3. Fourier Transform Infrared Spectroscopy (FTIR)
2.4. Thermo and Mechanical Analysis
2.5. Yerba Mate Extract Release
2.6. Antioxidant Activities (DPPH and ABTS)
2.7. Antibacterial Evaluation
2.8. Cytotoxic Evaluation
2.8.1. Elution Assay (Cytotoxicity Testing)
2.8.2. Determination of p65-NF-κB Protein
2.8.3. Wound Scratch Assay
2.8.4. Statistical Analyses
3. Results and Discussion
3.1. Characteristics of Blending the Extract with MFC at Different Stages
3.1.1. Microstructure
3.1.2. Yerba Mate Extract Release, Antioxidant, and Antibacterial Analysis
3.1.3. Mechanical and Thermal Properties
3.2. Characteristics of MFC with Extract Blended with Starch and Glycerine
3.2.1. Microstructure of Blending Various Materials within MFC
3.2.2. Extract Release, Antibacterial and Antioxidant Activities
3.2.3. Thermal and Mechanical Properties
3.2.4. Cell Activity Values
4. Conclusions
Supplementary Materials
Author Contributions
Funding
Conflicts of Interest
References
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Aliabadi, M.; Chee, B.S.; Matos, M.; Cortese, Y.J.; Nugent, M.J.D.; de Lima, T.A.M.; Magalhães, W.L.E.; de Lima, G.G. Yerba Mate Extract in Microfibrillated Cellulose and Corn Starch Films as a Potential Wound Healing Bandage. Polymers 2020, 12, 2807. https://doi.org/10.3390/polym12122807
Aliabadi M, Chee BS, Matos M, Cortese YJ, Nugent MJD, de Lima TAM, Magalhães WLE, de Lima GG. Yerba Mate Extract in Microfibrillated Cellulose and Corn Starch Films as a Potential Wound Healing Bandage. Polymers. 2020; 12(12):2807. https://doi.org/10.3390/polym12122807
Chicago/Turabian StyleAliabadi, Meysam, Bor Shin Chee, Mailson Matos, Yvonne J. Cortese, Michael J. D. Nugent, Tielidy A. M. de Lima, Washington L. E. Magalhães, and Gabriel Goetten de Lima. 2020. "Yerba Mate Extract in Microfibrillated Cellulose and Corn Starch Films as a Potential Wound Healing Bandage" Polymers 12, no. 12: 2807. https://doi.org/10.3390/polym12122807