Supramolecular Cyclodextrin-Based Hydrogels for Controlled Gene Delivery
AbstractControlled delivery of gene transfer vectors is a powerful strategy to enhance the temporal and spatial presentation of therapeutic agents in a defined target. Hydrogels are adapted biomaterials for gene delivery capable of acting as a localized depot of genes while maintaining the long term local availability of DNA vectors at a specific location. Supramolecular hydrogels based on cyclodextrins (CDs) have attracted considerable attention as potential biomaterials in a broad range of drug delivery applications. Their unique characteristics of thixotropicity and low cytotoxicity due to their production under mild conditions make them potential candidates to form injectable delivery systems. This work aims to provide an overview of the use of CD-based polypseudorotaxane hydrogels as controlled gene delivery systems for different applications in regenerative medicine. View Full-Text
Share & Cite This Article
Rey-Rico, A.; Cucchiarini, M. Supramolecular Cyclodextrin-Based Hydrogels for Controlled Gene Delivery. Polymers 2019, 11, 514.
Rey-Rico A, Cucchiarini M. Supramolecular Cyclodextrin-Based Hydrogels for Controlled Gene Delivery. Polymers. 2019; 11(3):514.Chicago/Turabian Style
Rey-Rico, Ana; Cucchiarini, Magali. 2019. "Supramolecular Cyclodextrin-Based Hydrogels for Controlled Gene Delivery." Polymers 11, no. 3: 514.
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.