A Review on Biological Synthesis of the Biodegradable Polymers Polyhydroxyalkanoates and the Development of Multiple Applications
, Purabi Bhagabati 2, Jessica De Micco 2, Ramesh Babu Padamati 2,3,* and Kevin O’Connor 1,3,*Round 1
Reviewer 1 Report
The manuscript entitled " Biological Synthesis of the Biodegradable Polymers Polyhy-droxyalkanoates and the Development of Multiple Applications " written by Bryan Dalton reported that Polyhydroxyalkanoates or PHAs, belong to a class of biopolyesters where the biodegradable PHA polymer is accumulated by microorganisms as intracellular granules known as carbonosomes. Like all new polymers PHA needs continuous technological developments in their production and material science developments to grow their market opportunities. The setup of end of life management (biodegradability, recyclability) system infrastructure is also critical to ensure that PHA and other biobased biodegradable polymers can be marketed with maximum benefits to society. The biobased nature and the biodegradability of PHAs mean they can be a key polymer in the materials sector of the future. The worldwide scale of plastic waste pollution demands a reformation of the current polymer industry, or humankind will face the consequences of having plastic in every step of the food chain and beyond. Below are some points that I would like to bring to the authors' attention:
- What is the meaning of the asterisk in Table 2, please mark it.
- In 3.2.2, the expression means 103 Mpa?
- Please unify the units in this literature.
- Please elaborate your own opinion more detailed.
Author Response
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Comment 1: What is the meaning of the asterisk in Table 2, please mark it. |
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Response 1: There is a mismatch in the reference, hence the whole row and its information is deleted in the revised manuscript. |
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Comment 2: In 3.2.2, the expression means 103 Mpa? |
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Response 2: The term I corrected as 103 MPa |
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Comment 3: Please unify the units in this literature. |
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Response 3: As suggested, the units are unified in the revised manuscript. |
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Comment 4: Please elaborate your own opinion more detailed. |
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Response 4: Done so within ‘Conclusions’ |
Reviewer 2 Report
The authors complete a nice manuscript about the synthesis and applications of PHAs. The introduction provides all the state of the art and update the reader about the literature. The chapters are well divided and complete, they provide references and a nice small introductions which help the reader.
My advice for the conclusions is to add some personal opinion, seen the experties of the authors would be nice to have some phrases looking into the future of these materials
I advice the authors to put a title in which the sense of review is more expressed: using terms like "review" or "an overlook" etc.
-in figure 1 and please check in all the other figures, it is missing the technique of imaging, even if in the text you said, the caption has to be self describing.
-figure 4 : if not taken from another paper, please draw it with chemdraw or a chemistry software, using arrows intead of equal etc
-figure 5: as figure 4, respecting the bond angles
Author Response
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Comment 1: My advice for the conclusions is to add some personal opinion, seen the experties of the authors would be nice to have some phrases looking into the future of these materials |
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Response 1: Done so within ‘Conclusions’ |
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Comment 2: I advice the authors to put a title in which the sense of review is more expressed: using terms like "review" or "an overlook" etc. |
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Response 2: The title is modified into “A Review on Biological Synthesis of the Biodegradable Polymers Polyhydroxyalkanoates and the Developement of Multiple Applications”. |
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Comment 3: -in figure 1 and please check in all the other figures, it is missing the technique of imaging, even if in the text you said, the caption has to be self describing. |
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Response 3: As suggested, the caption is changed to ‘Transmission electron micrograph showing granules of PHA accumulated in the bacterium P. putida CA-3 from styrene’. |
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Comment 4: -figure 4 : if not taken from another paper, please draw it with chemdraw or a chemistry software, using arrows intead of equal etc |
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Response 4: Figure 4 was made with BIOVIA Draw 21.1 version, and image is amended as per reviewer suggestion. |
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Comment 5: -figure 5: as figure 4, respecting the bond angles |
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Response 5: Unlike figure 4 this image was taken from reference #4 with copyright permission certificate obtained to publish. |
Round 2
Reviewer 1 Report
Accept in present form
