The Role of HPV in Head and Neck Cancer Stem Cell Formation and Tumorigenesis
Abstract
:1. Introduction
2. The Cancer Stem Cell Theory
3. Cancer Stem Cells in Head and Neck Cancer
3.1. Emerging Evidence of HNSCC Cancer Stem Cells
3.2. Unique Response to Therapy
3.3. Stem Cell Pathways for Tumorigenesis
3.3.1. Nanog
3.3.2. Notch
3.3.3. Oct-4
3.4. Cancer Stem Cellular Markers
4. Human Papilloma Virus in Oropharyngeal Head and Neck Cancer
4.1. Relationship of HPV with Cancer Stem Cells
4.2. HPVs Mechanism for Oncogenesis and CSC Formation
5. Conclusions
Author Contributions
Conflicts of Interest
References
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Swanson, M.S.; Kokot, N.; Sinha, U.K. The Role of HPV in Head and Neck Cancer Stem Cell Formation and Tumorigenesis. Cancers 2016, 8, 24. https://doi.org/10.3390/cancers8020024
Swanson MS, Kokot N, Sinha UK. The Role of HPV in Head and Neck Cancer Stem Cell Formation and Tumorigenesis. Cancers. 2016; 8(2):24. https://doi.org/10.3390/cancers8020024
Chicago/Turabian StyleSwanson, Mark S., Niels Kokot, and Uttam K. Sinha. 2016. "The Role of HPV in Head and Neck Cancer Stem Cell Formation and Tumorigenesis" Cancers 8, no. 2: 24. https://doi.org/10.3390/cancers8020024