Surgery of Primary Melanomas
Abstract
:1. Introduction
2. The Diagnosis of the Melanoma (Excisional Biopsy)
3. The Radical Surgery of the Primary Tumor
Breslow thickness [mm] | Clinical study | Patients(No.) | Margins [cm] | Overall survival (at years) | Ref. |
---|---|---|---|---|---|
French Cooperative Group | 336 | 2 vs. 5 | No difference(10-year) | [25,28] | |
≤2 | Swedish Melanoma Group | 989 | 2 vs. 5 | No difference(5-year) | [23,29] |
WHO Melanoma Group Trial No. 10 | 612 | 1 vs. 3 | No difference(10-year) | [30,31] | |
1–4 | Intergroup Melanoma Surgical Trial | 486 | 2 vs. 4 | No difference(6-year) | [26,32,33] |
≥2 | UK Melanoma Study Group | 900 | 1 vs. 3 | Not reported; hazard ratio for death was similar in both groups (5-year) | [27] |
Swedish Melanoma Trial Group | 1,000 | 2 vs. 4 | Final results not reported; preliminary results indicated no difference (5-year) | [34] |
4. Primary Melanoma of Specific Sites
4.1. Melanoma of Mucosal Surfaces
4.2. Subungual Melanoma of the Hand or Foot
4.3. Melanoma of the Face and Scalp
5. Ocular Melanoma
6. Final Considerations
References
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Rutkowski, P.; Zdzienicki, M.; Nowecki, Z.I.; Van Akkooi, A.C.J. Surgery of Primary Melanomas. Cancers 2010, 2, 824-841. https://doi.org/10.3390/cancers2020824
Rutkowski P, Zdzienicki M, Nowecki ZI, Van Akkooi ACJ. Surgery of Primary Melanomas. Cancers. 2010; 2(2):824-841. https://doi.org/10.3390/cancers2020824
Chicago/Turabian StyleRutkowski, Piotr, Marcin Zdzienicki, Zbigniew I. Nowecki, and Alexander C. J. Van Akkooi. 2010. "Surgery of Primary Melanomas" Cancers 2, no. 2: 824-841. https://doi.org/10.3390/cancers2020824