Next Article in Journal
VEGF and Pleiotrophin Modulate the Immune Profile of Breast Cancer
Next Article in Special Issue
Prognostic Significance of Melanoma Differentiation and Trans-Differentiation
Previous Article in Journal
Predictive and Prognostic Protein Biomarkers in Epithelial Ovarian Cancer: Recommendation for Future Studies
Previous Article in Special Issue
Surgery of Primary Melanomas
Article Menu

Export Article

Open AccessReview
Cancers 2010, 2(2), 955-969;

Systemic Therapy of Non-Resectable Metastatic Melanoma

Department of Dermatology, Venereology and Allergology, University Medical Center Mannheim, Ruprecht-Karl University of Heidelberg, Mannheim, Germany
Author to whom correspondence should be addressed.
Received: 8 March 2010 / Revised: 11 May 2010 / Accepted: 12 May 2010 / Published: 26 May 2010
(This article belongs to the Special Issue Current Concepts in the Diagnosis and Treatment of Cutaneous Melanoma)
Full-Text   |   PDF [123 KB, uploaded 26 May 2010]


In advanced metastatic melanoma (non-resectable stage III/IV), the prognosis still remains poor, with median survival times between six and twelve months. Systemic therapeutic approaches for metastatic melanoma include chemotherapy, immunotherapy, immunochemotherapy, small molecules and targeted therapy. In this review, we will focus on the various treatment modalities as well as new agents used for targeted therapy. View Full-Text
Keywords: melanoma; metastatic; chemotherapy; targeted therapy; small molecules melanoma; metastatic; chemotherapy; targeted therapy; small molecules
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

Share & Cite This Article

MDPI and ACS Style

Orouji, A.; Goerdt, S.; Utikal, J. Systemic Therapy of Non-Resectable Metastatic Melanoma. Cancers 2010, 2, 955-969.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics



[Return to top]
Cancers EISSN 2072-6694 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top