Arytenoid Fixation in Laryngeal Cancer: Radiological Pictures and Clinical Correlations with Respect to Conservative Treatments
AbstractBackground: The aim of this retrospective study was to identify different radiological features in intermediate–advanced laryngeal cancer (LC) associated with arytenoid fixation, in order to differentiate cases still safely amenable to conservative treatment by partial laryngectomy or chemoradiotherapy. Methods: 29 consecutive patients who underwent open partial horizontal laryngectomies (OPHLs), induction chemotherapy followed by radiotherapy in the case of >50% response (IC + RT) or total laryngectomy were classified as: pattern I (supraglottic LC fixing the arytenoid due to weight effect), pattern II (glottic LC involving the posterior paraglottic space and spreading toward the crico-arytenoid joint and infraglottic extension <10 mm), pattern III (glottic—infraglottic LC involving the crico-arytenoid joint and infraglottic extension >10 mm) and pattern IV (transglottic and infraglottic LC with massive crico-arytenoid unit involvement, reaching the hypopharyngeal submucosa). All glottic cancers treated with surgery were studied by a cross sectional approach. Results: A substantial agreement between the work-up and the pathology results has been obtained in each of the subcategories. Three-year disease-free survivals, local control and freedom from laryngectomy were significantly better in pattern II compared to pattern III–IV. Conclusions: LC showing fixed arytenoid due to weight effect or posterior paraglottic space involvement with infraglottic extension <10 mm assessed at the true vocal cord midline are still safely manageable by OPHL or IC + RT. View Full-Text
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Succo, G.; Cirillo, S.; Bertotto, I.; Maldi, E.; Balmativola, D.; Petracchini, M.; Gned, D.; Fornari, A.; Motatto, G.M.; Sprio, A.E.; Manca, A.; Crosetti, E. Arytenoid Fixation in Laryngeal Cancer: Radiological Pictures and Clinical Correlations with Respect to Conservative Treatments. Cancers 2019, 11, 360.
Succo G, Cirillo S, Bertotto I, Maldi E, Balmativola D, Petracchini M, Gned D, Fornari A, Motatto GM, Sprio AE, Manca A, Crosetti E. Arytenoid Fixation in Laryngeal Cancer: Radiological Pictures and Clinical Correlations with Respect to Conservative Treatments. Cancers. 2019; 11(3):360.Chicago/Turabian Style
Succo, Giovanni; Cirillo, Stefano; Bertotto, Ilaria; Maldi, Elena; Balmativola, Davide; Petracchini, Massimo; Gned, Dario; Fornari, Alessandro; Motatto, Gian M.; Sprio, Andrea E.; Manca, Andrea; Crosetti, Erika. 2019. "Arytenoid Fixation in Laryngeal Cancer: Radiological Pictures and Clinical Correlations with Respect to Conservative Treatments." Cancers 11, no. 3: 360.
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