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Cancers 2018, 10(5), 145;

[18F]FDG-PET/CT in Hodgkin Lymphoma: Current Usefulness and Perspectives

Nuclear Medicine Department, Institut Claudius Regaud, 31100 Toulouse, France
Centre de Recherches en Cancérologie de Toulouse (CRCT), UMR1037 INSERM, Université Toulouse III: Paul-Sabatier, ERL5294 CNRS, Université de Toulouse, 31100 Toulouse, France
Hématologie Clinique, CHU Dijon, 21000 Dijon, France
INSERM UMR1231, Université de Bourgogne Franche Comte, 21000 Dijon, France
Author to whom correspondence should be addressed.
Received: 9 April 2018 / Revised: 15 May 2018 / Accepted: 15 May 2018 / Published: 18 May 2018
(This article belongs to the Special Issue Hodgkin's Lymphoma)
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Functional imaging using 18-fluorodeoxyglycose ([18F]FDG) positron emission tomography combined with computed tomography (PET/CT) has become a major imaging modality in Hodgkin lymphoma. This imaging modality allows for a significant improvement in staging, increased sensitivity, which involves differentiating residual tumors from fibrosis during assessment, and highly impacts treatment decisions into new PET-driven strategies. This review presents the main scientific data concerning the current applications of [18F]FDG-PET/CT in Hodgkin lymphoma at baseline, interim, and the end of treatment evaluation along with the main PET-driven trials for therapeutic decisions. The emergence of total metabolic tumor volume as a new functional prognostic factor will also be discussed. View Full-Text
Keywords: Hodgkin Lymphoma; [18F]FDG; PET/CT; staging; treatment response; interim PET; total metabolic tumor volume Hodgkin Lymphoma; [18F]FDG; PET/CT; staging; treatment response; interim PET; total metabolic tumor volume

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Kanoun, S.; Rossi, C.; Casasnovas, O. [18F]FDG-PET/CT in Hodgkin Lymphoma: Current Usefulness and Perspectives. Cancers 2018, 10, 145.

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