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Cancers
Volume 10
Issue 11
10.3390/cancers10110462
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Review

Liquid Crystals: A Novel Approach for Cancer Detection and Treatment

by
Jayalakshmi Vallamkondu
1,2,*,
Edwin Bernard Corgiat
3,
Gollapelli Buchaiah
1,
Ramesh Kandimalla
4,5 and
P. Hemachandra Reddy
4,5,6,7,8,9,10,*
1
Department of Physics, NIT Warangal, Telangana 506004, India
2
Centre for Advanced Materials, NIT Warangal, Telangana 506004, India
3
Department of Cellular Biology, Emory University School of Medicine, Atlanta, GA 30322, USA
4
Garrison Institute on Aging, Texas Tech University Health Sciences Center, 3601 4th Street, MS 9424, Lubbock, TX 79430, USA
5
Neurology Department, Texas Tech University Health Sciences Center, 3601 4th Street, MS 9424, Lubbock, TX 79430, USA
6
Pharmacology and Neuroscience Department, Texas Tech University Health Sciences Center, 3601 4th Street, MS 9424, Lubbock, TX 79430, USA
7
Garrison Institute on Aging, South West Campus, Texas Tech University Health Sciences Center, 6630 S. Quaker Suite E, MS 7495, Lubbock, TX 79413, USA
8
Cell Biology and Biochemistry Department, Texas Tech University Health Sciences Center, 3601 4th Street, MS 9424, Lubbock, TX 79430, USA
9
Speech, Language and Hearing Sciences Department, Texas Tech University Health Sciences Center, 3601 4th Street, MS 9424, Lubbock, TX 79430, USA
10
Department of Public Health, Graduate School of Biomedical Sciences, 3601 4th Street, MS 9424, Lubbock, TX 79430, USA
*
Authors to whom correspondence should be addressed.
Cancers 2018, 10(11), 462; https://doi.org/10.3390/cancers10110462
Submission received: 1 October 2018 / Revised: 2 November 2018 / Accepted: 5 November 2018 / Published: 21 November 2018
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Abstract

Liquid crystals are defined as the fourth state of matter forming between solid and liquid states. Earlier the applications of liquid crystals were confined to electronic instruments, but recent research findings suggest multiple applications of liquid crystals in biology and medicine. Here, the purpose of this review article is to discuss the potential biological impacts of liquid crystals in the diagnosis and prognosis of cancer along with the risk assessment. In this review, we also discussed the recent advances of liquid crystals in cancer biomarker detection and treatment in multiple cell line models. Cases reviewed here will demonstrate that cancer diagnostics based on the multidisciplinary technology and intriguingly utilization of liquid crystals may become an alternative to regular cancer detection methodologies. Additionally, we discussed the formidable challenges and problems in applying liquid crystal technologies. Solving these problems will require great effort and the way forward is through the multidisciplinary collaboration of physicists, biologists, chemists, material-scientists, clinicians, and engineers. The triumphant outcome of these liquid crystals and their applications in cancer research would be convenient testing for the detection of cancer and may result in treating the cancer patients non-invasively.
Keywords: cancers; liquid crystals; biomarker; biosensor; antitumor drug cancers; liquid crystals; biomarker; biosensor; antitumor drug

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MDPI and ACS Style

Vallamkondu, J.; Corgiat, E.B.; Buchaiah, G.; Kandimalla, R.; Reddy, P.H. Liquid Crystals: A Novel Approach for Cancer Detection and Treatment. Cancers 2018, 10, 462. https://doi.org/10.3390/cancers10110462

AMA Style

Vallamkondu J, Corgiat EB, Buchaiah G, Kandimalla R, Reddy PH. Liquid Crystals: A Novel Approach for Cancer Detection and Treatment. Cancers. 2018; 10(11):462. https://doi.org/10.3390/cancers10110462

Chicago/Turabian Style

Vallamkondu, Jayalakshmi, Edwin Bernard Corgiat, Gollapelli Buchaiah, Ramesh Kandimalla, and P. Hemachandra Reddy. 2018. "Liquid Crystals: A Novel Approach for Cancer Detection and Treatment" Cancers 10, no. 11: 462. https://doi.org/10.3390/cancers10110462

APA Style

Vallamkondu, J., Corgiat, E. B., Buchaiah, G., Kandimalla, R., & Reddy, P. H. (2018). Liquid Crystals: A Novel Approach for Cancer Detection and Treatment. Cancers, 10(11), 462. https://doi.org/10.3390/cancers10110462

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