Next Article in Journal
Effect of Various Defects on 4H-SiC Schottky Diode Performance and Its Relation to Epitaxial Growth Conditions
Next Article in Special Issue
Programmable µChopper Device with On-Chip Droplet Mergers for Continuous Assay Calibration
Previous Article in Journal
Droplet and Particle Generation on Centrifugal Microfluidic Platforms: A Review
Previous Article in Special Issue
Generation of Ultra-Thin-Shell Microcapsules Using Osmolarity-Controlled Swelling Method

Microfluidic Droplet-Storage Array

by 1,2 and 2,*
Department of Instructive Biomaterials Engineering, MERLN Institute for Technology-Inspired Regenerative Medicine, Maastricht University, 6229 ER Maastricht, The Netherlands
Mesoscale Chemical Systems Group, MESA+ Institute, University of Twente, 7522 NB Enschede, The Netherlands
Author to whom correspondence should be addressed.
Micromachines 2020, 11(6), 608;
Received: 30 May 2020 / Revised: 19 June 2020 / Accepted: 22 June 2020 / Published: 23 June 2020
(This article belongs to the Special Issue Droplet Microfluidics)
A microfluidic droplet-storage array that is capable of the continuous operation of droplet formation, storing, repositioning, retrieving, injecting and restoring is demonstrated. The microfluidic chip comprised four valve-assisted droplet generators and a 3 × 16 droplet-storage array. The integrated pneumatically actuated microvalves enable the precise control of aqueous phase dispensing, as well as carrier fluid flow path and direction for flexible manipulating water-in-oil droplets in the chip. The size of droplets formed by the valve-assisted droplet generators was validated under various operating conditions such as pressures for introducing solutions and dispensing time. In addition, flexible droplet addressing in the storage array was demonstrated by storing droplets with various numbers and compositions in different storage units as well as rearranging their stored positions. Moreover, serial injections of new droplets into a retrieved droplet from a storage unit was performed to show the potential of the platform in sequential dosing on incubated droplet-based reactors at the desired timeline. The droplet-storage array with great freedom and flexibility in droplet handling could be applied for performing complex chemical and biologic reactions, especially in which incubation and dosing steps are necessary. View Full-Text
Keywords: microfluidics; droplet array; microvalve microfluidics; droplet array; microvalve
Show Figures

Figure 1

MDPI and ACS Style

Rho, H.S.; Gardeniers, H. Microfluidic Droplet-Storage Array. Micromachines 2020, 11, 608.

AMA Style

Rho HS, Gardeniers H. Microfluidic Droplet-Storage Array. Micromachines. 2020; 11(6):608.

Chicago/Turabian Style

Rho, Hoon S., and Han Gardeniers. 2020. "Microfluidic Droplet-Storage Array" Micromachines 11, no. 6: 608.

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

Back to TopTop