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Open AccessReview

Droplet and Particle Generation on Centrifugal Microfluidic Platforms: A Review

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School of Engineering and Sciences, Tecnológico de Monterrey, Ave. Eugenio Garza Sada 2501, Monterrey 64849, NL, Mexico
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Department of Mechanical and Aerospace Engineering, University of California Irvine, Irvine, CA 92697, USA
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Authors to whom correspondence should be addressed.
Micromachines 2020, 11(6), 603; https://doi.org/10.3390/mi11060603
Received: 20 April 2020 / Revised: 17 June 2020 / Accepted: 18 June 2020 / Published: 22 June 2020
The use of multiphase flows in microfluidics to carry dispersed phase material (droplets, particles, bubbles, or fibers) has many applications. In this review paper, we focus on such flows on centrifugal microfluidic platforms and present different methods of dispersed phase material generation. These methods are classified into three specific categories, i.e., step emulsification, crossflow, and dispenser nozzle. Previous works on these topics are discussed and related parameters and specifications, including the size, material, production rate, and rotational speed are explicitly mentioned. In addition, the associated theories and important dimensionless numbers are presented. Finally, we discuss the commercialization of these devices and show a comparison to unveil the pros and cons of the different methods so that researchers can select the centrifugal droplet/particle generation method which better suits their needs. View Full-Text
Keywords: droplet generation; particle generation; bubble generation; multiphase flows; centrifugal microfluidics droplet generation; particle generation; bubble generation; multiphase flows; centrifugal microfluidics
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MDPI and ACS Style

Azimi-Boulali, J.; Madadelahi, M.; Madou, M.J.; Martinez-Chapa, S.O. Droplet and Particle Generation on Centrifugal Microfluidic Platforms: A Review. Micromachines 2020, 11, 603.

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