Next Article in Journal
In-Situ Measurements in Microscale Gas Flows—Conventional Sensors or Something Else?
Previous Article in Journal
Editorial for the Special Issue on MEMS Accelerometers
Article Menu

Export Article

Open AccessArticle

A Facile Strategy for Visualizing and Modulating Droplet-Based Microfluidics

1
State Key Laboratory of Transducer Technology, Shanghai Institute of Microsystem and Information Technology, Chinese Academy of Sciences, Shanghai 200050, China
2
School of Information Science and Technology, ShanghaiTech University, Shanghai 201210, China
3
University of Chinese Academy of Sciences, Beijing 100049, China
4
Department of Chemistry, College of Science, Shanghai University, Shanghai 200444, China
*
Authors to whom correspondence should be addressed.
Micromachines 2019, 10(5), 291; https://doi.org/10.3390/mi10050291
Received: 27 March 2019 / Revised: 22 April 2019 / Accepted: 25 April 2019 / Published: 29 April 2019
  |  
PDF [1914 KB, uploaded 29 April 2019]
  |  

Abstract

In droplet-based microfluidics, visualizing and modulating of droplets is often prerequisite. In this paper, we report a facile strategy for visualizing and modulating high-throughput droplets in microfluidics. In the strategy, by modulating the sampling frequency of a flash light with the droplet frequency, we are able to map a real high frequency signal to a low frequency signal, which facilitates visualizing and feedback controlling. Meanwhile, because of not needing synchronization signals, the strategy can be directly implemented on any droplet-based microfluidic chips. The only cost of the strategy is an additional signal generator. Moreover, the strategy can catch droplets with frequency up to several kilohertz, which covers the range of most high-throughput droplet-based microfluidics. In this paper, the principle, setup and procedure were introduced. Finally, as a demonstration, the strategy was also implemented in a miniaturized picoinjector in order to monitor and control the injection dosage to droplets. We expect that this facile strategy supplies a low-cost yet effective imaging system that can be easily implemented in miniaturized microfluidic systems or general laboratories. View Full-Text
Keywords: microfluidics; droplets; high-throughput; modulate microfluidics; droplets; high-throughput; modulate
Figures

Figure 1

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

Supplementary material

SciFeed

Share & Cite This Article

MDPI and ACS Style

Gao, Z.; Peng, H.; Zhu, M.; Wu, L.; Jia, C.; Zhou, H.; Zhao, J. A Facile Strategy for Visualizing and Modulating Droplet-Based Microfluidics. Micromachines 2019, 10, 291.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Micromachines EISSN 2072-666X Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top