Fabrication of 512-Channel Geometrical Passive Breakup Device for High-Throughput Microdroplet Production
Abstract
:1. Introduction
2. Materials and Methods
2.1. Design of Microfluidic Device
2.2. Fabrication Process for 512-Channel Geometrical Passive Breakup Device
2.3. Experimental Set-Up for Microfluidic Device
2.4. Preparation of Chitosan Microspheres with Fabricated Microfluidic Device
3. Results and Discussion
4. Conclusions
Author Contributions
Funding
Conflicts of Interest
References
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Specifications | Width (μm) |
---|---|
A: Width of input A | 1000 |
B: Width of input B | 1000 |
C: Width of first T-junction | 500 |
D: Width of second T-junction | 540 |
E: Width of third T-junction | 330 |
F: Width of fourth T-junction | 200 |
G: Width of fifth T-junction | 130 |
H: Width of sixth T-junction | 80 |
I: Width of seventh T-junction | 50 |
J: Width of eighth T-junction | 30 |
K: Width of ninth T-junction | 30 |
T: Thickness of the device | 40 |
Geometry and Material | Continuous Phase | Droplet Size (μm) | Frequency (Hz) | |
---|---|---|---|---|
Water in oil | Channel array, silicon | Kerosene with monolaurate | 21 | −5300 (est.) |
T-junction, acrylated urethane | Decane, tetradecane, and hexadecane with Span 80 | 10–350 | 20–80 | |
T-junction, PMMA | High-oleic sunflower oil | 100–350 | 10–2500 | |
T-junction, PDMS | C14F12 with C6F13(CH2)2OH | 7.5 nl | 2 | |
Shear-focusing, PDMS | Oleic acid | 13–35 | 15–100 |
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Kim, C.M.; Kim, G.M. Fabrication of 512-Channel Geometrical Passive Breakup Device for High-Throughput Microdroplet Production. Micromachines 2019, 10, 709. https://doi.org/10.3390/mi10100709
Kim CM, Kim GM. Fabrication of 512-Channel Geometrical Passive Breakup Device for High-Throughput Microdroplet Production. Micromachines. 2019; 10(10):709. https://doi.org/10.3390/mi10100709
Chicago/Turabian StyleKim, Chul Min, and Gyu Man Kim. 2019. "Fabrication of 512-Channel Geometrical Passive Breakup Device for High-Throughput Microdroplet Production" Micromachines 10, no. 10: 709. https://doi.org/10.3390/mi10100709