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Toxins 2018, 10(11), 453; https://doi.org/10.3390/toxins10110453

Accumulation of Dinophysis Toxins in Bivalve Molluscs

Centro de Investigacións Mariñas, Pedras de Corón s/n, 36620 Vilanova de Arousa, Spain
Received: 25 September 2018 / Revised: 19 October 2018 / Accepted: 23 October 2018 / Published: 2 November 2018
(This article belongs to the Special Issue Dinophysis Toxins: Distribution, Fate in Shellfish and Impacts)
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Abstract

Several species of the dinoflagellate genus Dinophysis produce toxins that accumulate in bivalves when they feed on populations of these organisms. The accumulated toxins can lead to intoxication in consumers of the affected bivalves. The risk of intoxication depends on the amount and toxic power of accumulated toxins. In this review, current knowledge on the main processes involved in toxin accumulation were compiled, including the mechanisms and regulation of toxin acquisition, digestion, biotransformation, compartmentalization, and toxin depuration. Finally, accumulation kinetics, some models to describe it, and some implications were also considered. View Full-Text
Keywords: okadaic acid; pectenotoxins; Dinophysis toxins; accumulation; digestion; biotransformation; compartmentalization; depuration; kinetics okadaic acid; pectenotoxins; Dinophysis toxins; accumulation; digestion; biotransformation; compartmentalization; depuration; kinetics
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).
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Blanco, J. Accumulation of Dinophysis Toxins in Bivalve Molluscs. Toxins 2018, 10, 453.

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