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Suppressive Effects of Tea Catechins on Breast Cancer

1
Tea Research Institute, Zhejiang University, # 866 Yuhangtang Road, Hangzhou 310058, China
2
National Tea and Tea product Quality Supervision and Inspection Center (Guizhou), Zunyi 563100, China
*
Author to whom correspondence should be addressed.
Nutrients 2016, 8(8), 458; https://doi.org/10.3390/nu8080458
Received: 15 June 2016 / Revised: 20 July 2016 / Accepted: 22 July 2016 / Published: 28 July 2016
(This article belongs to the Special Issue Polyphenols for Cancer Treatment or Prevention)
Tea leaf (Camellia sinensis) is rich in catechins, which endow tea with various health benefits. There are more than ten catechin compounds in tea, among which epigallocatechingallate (EGCG) is the most abundant. Epidemiological studies on the association between tea consumption and the risk of breast cancer were summarized, and the inhibitory effects of tea catechins on breast cancer, with EGCG as a representative compound, were reviewed in the present paper. The controversial results regarding the role of tea in breast cancer and areas for further study were discussed. View Full-Text
Keywords: Camellia sinensis; anticancer; antioxidant; signaling pathway; anti-proliferation; DNA methylation; metastasis Camellia sinensis; anticancer; antioxidant; signaling pathway; anti-proliferation; DNA methylation; metastasis
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Xiang, L.-P.; Wang, A.; Ye, J.-H.; Zheng, X.-Q.; Polito, C.A.; Lu, J.-L.; Li, Q.-S.; Liang, Y.-R. Suppressive Effects of Tea Catechins on Breast Cancer. Nutrients 2016, 8, 458.

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