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Review

Natural Compounds and Their Potential in Eating-Related Aspects of Mental Health Disorders

1
School of Health and Rehabilitation, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China
2
Division of Clinical Pharmacology, Rudolf Boehm Institute for Pharmacology and Toxicology, Leipzig University, 04107 Leipzig, Germany
3
Rudolf Boehm Institute for Pharmacology and Toxicology, Leipzig University, 04107 Leipzig, Germany
*
Author to whom correspondence should be addressed.
These authors contributed equally to this work.
Nutrients 2025, 17(14), 2383; https://doi.org/10.3390/nu17142383
Submission received: 26 June 2025 / Revised: 16 July 2025 / Accepted: 17 July 2025 / Published: 21 July 2025
(This article belongs to the Special Issue Eating and Mental Health Disorders)

Abstract

Background and Objectives: Mental health and healthy eating are inextricably linked by bi-directional interaction. As pharmacological interventions for eating disorders and mental illness have limited efficacy and are associated with significant side effects, natural compounds traditionally used in these fields represent an extremely rich source for potential future drugs. This review aims to summarise complex and/or specific pharmacological and clinical effects of mixed compositions and individual compounds derived from Rosmarinus officinalis, Ginkgo biloba, and Bupleurum chinense as well as from Berberis vulgaris and other berberine (BBR)-containing plants, which have been traditionally used for eating and mental health purposes. Results and Conclusions: The data on favoured natural compounds and main ingredients of compound mixtures presented here could provide new impetus for preventive or targeted supplementary treatment, potential drug development, and the design of new compound congeners with improved target spectrum and potency in mental health disorders and eating-related issues. Contemporary methodological development steps in this direction are then proposed.
Keywords: mental health disorders; eating disorders; Rosmarinus officinalis; Ginkgo biloba; Bupleurum chinense; berberine; gut-brain axis mental health disorders; eating disorders; Rosmarinus officinalis; Ginkgo biloba; Bupleurum chinense; berberine; gut-brain axis

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MDPI and ACS Style

Ma, W.; Regenthal, R.; Krügel, U. Natural Compounds and Their Potential in Eating-Related Aspects of Mental Health Disorders. Nutrients 2025, 17, 2383. https://doi.org/10.3390/nu17142383

AMA Style

Ma W, Regenthal R, Krügel U. Natural Compounds and Their Potential in Eating-Related Aspects of Mental Health Disorders. Nutrients. 2025; 17(14):2383. https://doi.org/10.3390/nu17142383

Chicago/Turabian Style

Ma, Wenbin, Ralf Regenthal, and Ute Krügel. 2025. "Natural Compounds and Their Potential in Eating-Related Aspects of Mental Health Disorders" Nutrients 17, no. 14: 2383. https://doi.org/10.3390/nu17142383

APA Style

Ma, W., Regenthal, R., & Krügel, U. (2025). Natural Compounds and Their Potential in Eating-Related Aspects of Mental Health Disorders. Nutrients, 17(14), 2383. https://doi.org/10.3390/nu17142383

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