Next Article in Journal
Effects of Nut Consumption on Blood Lipids and Lipoproteins: A Comprehensive Literature Update
Previous Article in Journal
Lactose and Galactose Content in Spanish Cheeses: Usefulness in the Dietary Treatment of Patients with Galactosaemia
 
 
Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
Journals
Nutrients
Volume 15
Issue 3
10.3390/nu15030595
Review Report
nutrients-logo
Submit to this Journal Review for this Journal Propose a Special Issue
► Article Menu

Article Menu

share Share announcement Help format_quote Cite question_answer Discuss in SciProfiles
Article
Peer-Review Record

Low Free Triiodothyronine as a More Sensitive Predictor of Survival Than Total Testosterone among Dialysis Men

Nutrients 2023, 15(3), 595; https://doi.org/10.3390/nu15030595
by Ksymena Leśniak 1,*, Aleksandra Rymarz 1, Maria Sobol 2 and Stanisław Niemczyk 1
Reviewer 1: Anonymous
Reviewer 2:
Zhenlei Wang
Nutrients 2023, 15(3), 595; https://doi.org/10.3390/nu15030595
Submission received: 18 December 2022 / Revised: 11 January 2023 / Accepted: 20 January 2023 / Published: 23 January 2023
(This article belongs to the Section Clinical Nutrition)

Round 1

Reviewer 1 Report

A study was done to demonstrate a correlation between testosterone and Triiodothyronine with dialysis in men. Authors found that lower levels of Triiodothyronine are associated with poor prognosis. Overall, the data supports their conclusion, and the methods are described well. Previous studies have already shown that kidney defects result in the deterioration of thyroid hormones. This particular study confirms this in patients that were admitted to one hospital in Poland. Hence, the overall impact and novelty are limited. Some suggestions to improve the manuscript.

1) It is suggested to change the title into a statement rather than a question.

2) Add Triiodothyronine levels of control/healthy parties that belong to the same ethnicity

3) Mention any co-morbidities that the patients have especially fr the one that died

 

Author Response

Please see the attachment.

Author Response File: Author Response.docx

Reviewer 2 Report

By using appropriate statistical analysis, this manuscript illustrates that low free triiodothyronine acts as a more sensitive predictor of survival than total testosterone in men on dialysis. In general, the trial design and statistical methods of this cohort study are scientific and reasonable. Apart from this, I have a few minor issues that need to be addressed:

MINOR CONCERNS

1)     The manuscript provided a detailed description of the association between T3 and CKD in the background section, but did not provide an adequate description of the association between total testosterone levels and dialysis patients.

2)     The exclusion criteria are described in detail in the text. The inclusion criteria should be appropriately described on this basis.

3)     I suggest that the discussion section should include an exploration of the potential mechanisms by which thyroid hormones affect death in dialysis patients.

4)     The manuscript did not mention the calculation of sample size, I recommend that the author present the result based on statistics.

5)     I recommend streamlining the number of keywords to less than 5.

Author Response

Please see the attachment.

Author Response File: Author Response.docx

Back to TopTop