Alcohol, Coffee, and Milk Intake in Relation to Epilepsy Risk
Abstract
:1. Introduction
2. Methods
2.1. SNP Selection
2.2. Outcome Data Sources
2.3. Statistical Analyses
3. Results
3.1. Selection of Genetic Variants
3.2. MR Analysis
4. Discussion
Strengths and Limitations
5. Conclusions
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Datasets | Ancestry | Sample Size | Consortium |
---|---|---|---|
Outcome | |||
Epilepsy | ~86% Europeans | 15,212 cases/29,677 controls | ILAE consortium |
Epilepsy | Europeans | 4588 cases/144,780 controls | FinnGen consortium R4 release |
Exposure | |||
Alcohol | Europeans | 941,280 individuals | GWAS and Sequencing Consortium of Alcohol and Nicotine use (GSCAN) |
Coffee | Europeans | 375,833 individuals | UK biobank and US cohorts |
Milk | Europeans | 73,715 individuals | Copenhagen General Population Study |
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Zhang, Z.; Wang, M.; Yuan, S.; Liu, X. Alcohol, Coffee, and Milk Intake in Relation to Epilepsy Risk. Nutrients 2022, 14, 1153. https://doi.org/10.3390/nu14061153
Zhang Z, Wang M, Yuan S, Liu X. Alcohol, Coffee, and Milk Intake in Relation to Epilepsy Risk. Nutrients. 2022; 14(6):1153. https://doi.org/10.3390/nu14061153
Chicago/Turabian StyleZhang, Zhizhong, Mengmeng Wang, Shuai Yuan, and Xinfeng Liu. 2022. "Alcohol, Coffee, and Milk Intake in Relation to Epilepsy Risk" Nutrients 14, no. 6: 1153. https://doi.org/10.3390/nu14061153
APA StyleZhang, Z., Wang, M., Yuan, S., & Liu, X. (2022). Alcohol, Coffee, and Milk Intake in Relation to Epilepsy Risk. Nutrients, 14(6), 1153. https://doi.org/10.3390/nu14061153