Bee Pollen: Clinical Trials and Patent Applications
Abstract
:1. Introduction
2. Method
3. Clinical Trials
3.1. Prostatitis Diseases
3.2. Cancer Diseases
3.3. Allergic Diseases
3.4. Skin Diseases
4. Patents of Bee Pollen
4.1. Prostatitis Diseases
4.2. Diabetes Disease β
4.3. Immunity-Related Disorders
4.4. Chronic Diseases
Inventor | Country | Ingredients/Patent Form | Title/Patent Number/Patent Office | Features and Benefits | References |
---|---|---|---|---|---|
Ding, H. | China | Parts of raw materials by weight: 20–30 bee pollen, 20–30 bee placenta, 10–15 propolis, 20–25 royal jelly, 20–30 honey, 10–15 Rabdosia rubescens, 5–10 Pseudo-ginseng, 5–10 Ganoderma applanatum pat, 3–8 Lucid Ganoderma, 5–10 Acanthopanax, 3–8 peach kernels, 3–8 Rheum officinale, and 3–8 cassia twig/ND | Bee product emulsion for preventing cancer/CN 103239523 A/CN | Reduce inflammation, promote cancer resistance. | [114] |
Yu, N. | China | Bee pollen, Ganoderma powder, soya lecithin, and melatonin/tablet or capsule | A series of compound health foods and its preparation method/CN 1277028 A/CN | Anti-tumor, reducing lipids. | [115] |
Chen, J. | China | By wt. parts: 6–8 Urtica fissa herb, 10–16 bioflavonoid, 7–11 Achillea millefolium, 3–7 Lycium chinense and/or 2–4 bee pollen, Lycium barbarum fruit, 5–9 Foeniculum vulgare fruit, 12–16 Salvia miltiorrhiza root, 4–8 Dioscorea opposita and/or Dioscorea batatas rhizome peel, 10–14 calcium carbonate, 2–6 Panax ginseng ext., and 5–7 Momordica charantia fruit powder/ND | A kind of natural additive for foodstuffs/CN 108420070 A/CN | Prevents cancer, lowers blood lipids and blood glucose. | [116] |
Xiong, B. | China | Bee pollen, pine pollen, semen, natural calculus bovis, radix euphorbiae lantu, airpotato yam rhizome, tripterygium hypoglaucum, medical stone, momordicae, cortex cinnamomi, realgar, arsenic, processed semen strychni, bulb of edible tulip, dried lacquer, raw rhizoma pinelliae, garden balsam seeds, venenum bufonis, euphorbia kansui, euphorbia pekinensis roots, roots and leaves of wikstroemia indica, moleplant seed, rhizoma anemarrhenae, muskmelon pedicel, chalcanthite, gamboge, borneol, pseudobulbus cremastrae seu pleiones, semen pharbitidis, seaweed, kelp, roasted pangolin, white muscardine silkworm, sea clam powder, dragon bone and conch shell, ND | Preparation method of external navel plaster for adjuvant therapy for cancer/CN 112755125 A/CN | It is utilized as an auxiliary treatment for cancer. | [117] |
Yu, J.; Wei, Y. | China | Parts by weight: 0.3–0.5 bee pollen, 100–120 rice, 8–12 wheat grass, 8–12 celery, 4–8 melon seeds, 4–8 lemon, 4–8 honey, 6–10 Ziziphus Jujuba, 4–5 wheat flour, 0.5–0.7 black rice powder, 0.4–0.6 corn meal, 0.6–1 Mori Folium, 0.2–0.3 polygonum grass, 0.2–0.4 Glycyrrhiza uralensis Fisch, and water/ND | Celery health sake and its brewing method/CN 106554886 A/CN | Cancer inhibition, prevention of cardiovascular diseases, reducing blood lipids and blood sugar. | [118] |
Huang, F. | China | Parts by weight: 20–70 bee pollen, 30–120 stearoyl lactate, 30–130 biological flavone, 20–140 carragheen, 30–120 pickled red pepper, 30–150 hyacinth bean, 20–80 yellow tribute green pepper, 10–60 kudzu-vine root powder, 10–65 Radix Salviae Miltiorrhizae, 10–75 dietary fiber/ND | Kind of environmentally friendly food additive/CN 108294287 A/CN | Anticancer, antioxidant, anti-corrosion, reducing blood lipids and hypoglycemia. | [119] |
Wang, S. | China | By wt. parts: 1.40–2 bee pollen, 24–26 pork, 36–38 asparagus, 4.50–5.50 green Chinese onion, 1.40–1.60 coriander, 0.06–0.010 monosodium glutamate, 1.10–1.30 sodium chloride, 1.10–1.30 peanut oil, 1–1.50 Auricularia auricula, 0.30–0.50 grape seed oil, and 0.25–0.35 soy sauce/dumpling | Asparagus dumpling with healthcare function/CN 108272000 A/CN | Prevents cancer cells from dividing and growing, accelerates detoxification, lowers blood pressure, and improves cardiovascular functions. | [120] |
Liu, G. | China | Parts of raw materials by weight: 80–120 Melissa pollen, 30–60 castor bean, 200–400 egg, 3–8 bee venom, 30–60 propolis, and 200–400 honey/powder | A traditional Chinese medicinal composition for treatment of breast disease and its preparation method/CN 105380982 A/CN | Good therapeutic impact in the treatment of breast diseases, particularly breast cancer, neoplasms, and hyperplasia. Low cost; it is used as a dietary treatment once a day; no side effects. | [110] |
Zheng, J. | China | Parts by weight: 40–100 wall-broken bee pollen, 20–60 wall-broken Ganoderma lucidum spore powder, 80–150 Lycium barbarum fruit ext., and 5–30 western medicine such as chlorambucil, busulfan, melphalan/capsule or tablet | Pharmaceutical composition with anti-tumor activity, and its preparation/CN 105056238 A/CN | It has anti-tumor activity. | [111] |
Zhang, L. | China | Parts of raw materials by weight: 45 bee pollen, 35 parts of Salviae miltiorrhizae, and 20 kudzuvine root/powder | Pharmaceutical composition of Salvia miltiorrhiza and bee product/CN 103800433 A/CN | Effective for cardiovascular patients. | [113] |
Wu, J | China | Parts by weight through soaking in Chinese liquor: 15–30 pollen pini 20–40 honeybee room, 20–30 Giant salamander bone, and 10–20 Ampelopsis grossdentata/ND | One kind of anti-aging health wine and its preparation method/107034106 A/CN | Tumor inhibition, improves gastrointestinal functions, protect liver, and anti-aging impact. | [121] |
4.5. Microbial Diseases
4.6. Applications in Food Industry
4.7. Cosmetic Applications
5. Concluding Remarks and Future Perspectives
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Inventor | Country | Ingredients/Patent Form | Title/Patent Number/Patent Office | Features and Benefits | References |
---|---|---|---|---|---|
Xu, Y. | China | Rape bee polle ND | Rape flower alkali and application thereof/CN 106,366,014 A/CN | Inhibitory effect on prostatitis (in vitro) | [43] |
Chen, G.; et al. | China | Bee pollen of Brassica, Poria, Semen Persicae, Ramulus Cinnamomi, Cortex Moutan, and Radix Paeoniae Alba/Suspension, powder, drop, or solution | A Chinese medicinal prescription for treating benign prostatic hyperplasia/CN 101,590,126 A/CN | Reducing prostate volume and improving symptoms of lower urinary tract; can be used to treat some diseases related to prostatic hyperplasia, such as prostatic hyperplasia, syndromes of the lower urinary tract accompanied by prostatic hyperplasia, and other syndromes of the lower urinary tract. | [44] |
Hu, A. | China | Bee pollen, pine pollen, Chinese chive seed, raspberry, medlar, Lophatherum gracile, honeysuckle, licorice and orange peel, chestnut flour, carrot powder, mung bean flour, Semen Coicis powder, lotus seed powder, lycopene powder, spirulina powder, wakame powder, and vitamin C powder/ND | A prostate dietetic therapy formula or replacement product/CN 103,622,006 A/CN | Reduce the incidence of prostate-related disorders. | [51] |
Gou, C. | China | Bee pollen extract, Maca extract, yak penis extract, Tibetan sheep kidney extract, silkworm chrysalis extract, Lumbricus extract, trepang extract, Colla corii asini extract, bee milk extract, black wolfberry extract, an enzyme, omega-3 fatty acid, lycopene, zinc, and similar are used as raw materials/tablets | Lepidium meyenii-containing kidney-tonifying and prostate disease-treating tablet/CN 104,984,330 A/CN | Treatment for male sexual dysfunction, benign prostatic hyperplasia, prostatitis, and discomfort. | [52] |
He, P.; Liu, L.; Zhang, Q.; Zhang, Y. | China | Parts by weight: 6 bee pollen, 10 pilose antler, 10 bull penis, 10 deer penis, 10 Poria cocos, 8 Chinese yam, 6 dandelion, 10 Chinese chive seed, 10 golden cypress, 6 dogwood, 6 cowherb seed, 8 pine nut, 10 oyster, 8 Cistanche, 4 chestnut, 4 ginkgo, 6 wolfberry fruit, and 25 honey/ND | Functional nutritional food for improving male sexual function and preparation method thereof/CN 113,197,301 A/CN | Minimizing the impact of prostate inflammation on sexual function. Improving male sexual function via enhancing sperm quality, increasing patients’ erection firmness, extending sexual life, and increasing female satisfaction. | [53] |
Ma, H.; Wang, Y.; Kuang, H.; Lu, X. | China | 80–90% rape bee pollen, 5–7% honeycomb extract, 0.15–0.30% propolis, 2–4% honeysuckle, 2–3% dandelion, 2–3% Chinese violet, and 2–3% wild chrysanthemum/capsule | Capsule for treating prostate and preparation method thereof/CN 111,228,369 A/CN | Used as treatment for prostate disease. | [54] |
Qian, Z. | China | 50% bee pollen, 30–70% drone pupa, and 40% queen bee | A health care product for inhibiting prostate hyperplasia and its preparation method, containing male pupa apis, larva of queen bee, and/or pollen/CN 1,432,370 A/CN | Inhibiting prostate hyperplasia. | [55] |
Jiang, M.; Jiang, L. | China | Bee pollen and honey/bee pollen honeyed pill | Bee pollen honeyed pill and its preparation method/CN 1,596,710 A/CN | Good for prostate patients. | [56] |
Bai, W. A. | China | 35–50% bee pollen, 35–50% propolis powder, and 10–15% adjuvant material/capsule | Capsule prepared from propolis powder and bee pollen and its preparation method/CN 101,116,497 A/CN | Rehabilitation for many diseases including prostatic hyperplasia, prostatitis, and prostate diseases. | [57] |
Wu, X.; Wu, Z. | China | Auxiliary material (by wt. parts): 15–25 soybeanbean, 8–12 flaxseed, 6–9 tomato, 15–25 snow pear, 10–20 tea oil, 8–12 bee pollen, and 10–20 tea leaves powder/raw materials | Preparation method for prostate health tea/CN 107,372,942 A/CN | Effective for prostate healthcare. Non-toxic, the cost is inexpensive, and is available as raw materials. | [58] |
Liu, Y. | China | wt. parts: 60 bee pollen, 30 propolis, 20 royal jelly freeze-dried powder/raw materials | A Kind of bee product composition and preparation method thereof/CN 108,902,852 A/CN | Good effect in the treatment of prostatic disorders. | [45] |
Li, Z. | China | wt. parts: 2–4.50 bee pollen 1.5–3.5 propolis, 2–4.5 royal jelly, and 1.5–3.8 queen bee grub, 2–4 starch, 0.2–0.8 dextrin, 0.2–0.8 powder sugar/coated tablets | Health food of purified propolis, royal jelly, bee pollen, and queen bee grub for treating prostatic diseases/CN 101,480,412 A/CN | Treat prostatitis and prostatic hypertrophy. | [46] |
Mao, R. | China | 50% bee pollen form Cole, 35% Pueraria root powder, and 15% auxiliary materials including microcrystalline cellulose, lactose, sodium carboxymethyl cellulose, and starch/tablet | Health tablet containing rape bee pollen and Maca powder and preparation method thereof/CN 103,622,020 A/CN | Preventing prostate from hypertrophy, controlling internal secretion sexual function, and increasing prostate function, fertility. | [47] |
Li, Z.; Wu, K.; Tan, Z. | China | wt. parts: 100–150 bee pollen, 50–100 propolis, 20–80 queen bee larva, 20–80 royal jelly, 50–100 honey, and 100–150 Parasitic loranthus extract/ND | Method for manufacturing health composition of bee products and Taxillus chinensis/CN 101,836,736 A/CN | Increasing the prostatic, sexual, and gastrointestinal functions. | [48] |
Guo, L. | China | 80% bee pollen (rape pollen or corn pollen) and 20% Cucurbita moschata/powder | Method for manufacturing pollen product for treating chronic prostatitis, prostate dysfunction, and prostatauxe/CN 101,869,592 A/CN | Treating chronic prostatitis, functional disorders of the prostate and prostate hypertrophy. | [49] |
Wang, M.; Lei, Q. | China | Lucid Ganoderma–pollen liquor consists of 100 parts ethanol water of 25~60% (weight), 3~15 parts bee pollen, 1~10 part Ganoderma, 0.1~0.3 part Fructus Lycii, 0.1~0.2 part organic acid esters, 0.05~0.1 part sweetening agent/alcoholic medical health drink | A medicated liquor containing Ganoderma and bee pollen/CN 1,096,444 A/CN | Effective for conditions such as prostate hyperplasia and constipation. | [50] |
Inventor | Country | Ingredients (Parts by Weight)/Patent Form | Title/Patent Number/Patent Office | Features and Benefits | References |
---|---|---|---|---|---|
Cheng, Y.; et al. | China | By weight of: 50–70 Trichosanthes kirilowii, 3–8 Lilii Bulbus, 5–8 mulberry, 3–5 glutinous rice flour, 5–7 Sargassum powder, 10–15 Puerariae radix lyophilized powder, 1–2 strawberry essence, 3–6 bee, 1:5–7:3–5 propolis dry powder, broken bee pollen, and royal jelly powder/powder | A hypotensive and hypoglycemic Fructus trichosanthis powder and processing method thereof/CN 105,963,566 A/CN | Assists treatment of diabetes. Long-term consumption can improve patient’s immunity and promote health. | [65] |
Zhang, K. | China | By weight part: 45 bee pollen, 35 Trichosanthes root, and 20 root of kudzu vine/powder | Medicine composition containing Radix trichosanthis and bee product/CN 103,893,254 A/CN | Decreasing blood glucose and lipid levels. | [66] |
Pang, Y. | China | By weight part: 45 bee pollen, 35 Philippine flemingia root, 33 Radix Astragali, and 20 Radix Puerariae/ powder | One kKind of pharmaceutical composition with bee product and Flemingia/CN 104,398,566 A/CN | Effective in lowering lipid and glucose levels. | [63] |
Ma, N.; Chai, H. | China | Bee pollen, papain, amylase, lipase, saccharifying enzyme, Sargassum extract, Panama extract, Citrus reticulata polyphenol, tetrahydropiperine, Gynostemma pentaphyllum, Cyclocarya paliurus, Radix Trichosanthis, Rhizoma Coptidis, Litchi chinensis, Trifolium pratense, Agrimonia pilosa, Portulaca oleracea, Ophiopogon japonicus, Momordica charantia, anion powder, IR ceramic powder, and heat-sensitive agent/ND | External composition for treating diabetes mellitus and preparation method thereof/CN 106,237,315 A/CN | Regulating blood sugar. | [67] |
Wu, G.; Fan, J.; Wang, F. F. | China | Weight part: 3–7 bee pollen, 22–27 ginger, 32–40 Polygonati Rhizoma, 12–17 medlar, 5–13 Puerariae Radix powder, 0.8–2.5 magnesium stearate/tablet | One kind of fine white ginger compound health buccal tablet and its preparation method/CN 106,539,022 A/CN | Regulating blood glucose level, improving immunity, and anti-aging effect. | [68] |
Liu, X.; Liu, H.; Liu, H.; et al. | China | By wt. part: 20–40 bee pollen and 20–60 propolis/powder | A blood sugar-reducing propolis pollen and preparation method thereof/CN 113,080,408 A/CN | Significant impact in reducing blood glucose. For diabetic patients. No side effects. | [62] |
Gao, C. | China | Raw materials by weight: 5–15 g bee pollen, 5–15 g Chinese yam, 4–15 g Poria cocos, 5–15 g of dried orange peel, 4–15 g oyster, 4–15 g raspberry, 4–15 g radish seed, 3–12 g Cordyceps militaris, 5–15 g dandelion, 5–15 g Perilla frutescens, 5–15 g gorgon fruit, 5–15 g perilla seed, 5–15 g coix seed, 5–15 g purslane, 5–15 g Polygonatum odoratum, 2–10 g Angelica dahurica, 5–15 g lily, 1–10 g donkey-hide gelatin, 5–15 g lotus seed, 2–10 gjujube, 2–10 g dark plum, one cactus, 0.5–5 g pseudo-ginseng, 1–5 g safflower carthamus, 1–5 g Astragalus mongholicus, 2–10 g Oldenlandia diffusa, 2–10 g barbed skullcap herb, 10–20 gRhizoma polygonati, 2–12 g kudzu root, 10–20 g fleece-flower root, 4–15 gbalsam pear, 4–15 g medlar, 2–10 g Potentilla discolor, 4–15 g dwarf lilyturf tuber, and 2–15 g of mulberry leaf/powder | Medicine for treating diabetic complications and preparation method thereof/CN 112,451,629 A/ CN | Treatment for complications of diabetes. It has no side effect, with good impact on lowering appetite. | [69] |
Yao, Z. | China | Milk tea has raw material of prebiotic content by following parts by weight: 4–8 bee pollen, 10–20 prebiotic compositions, 10–15 skimmed milk power, 20–30 passionfruit, 80–100 tea base, 20–30 ginkgo leaf, 4–8 juice powder, 4–8 yeast, 4–8 dragonfruit, 4–8 Gynura procumbens (Lour.) Merr extract, 8–12 Pleurotus eryngii, 1–5 lower of kudzuvine, 1–5 Radix bardanae, 1–5 bluish dogbane, 1–5 cassia seed/ND | With prebiotic composition milk tea and its preparation method/CN 107,114,507 A/CN | Effective impact on regulating blood glucose level, decreasing lipid level, and enhancing digestion. | [70] |
Bin, Y. | China | Weight ratio: 10–15 bee pollen,15–20 dried rhizome of Rehmannia rich in selenium, 5–10 bee glue powder, 8–12 Radix paeoniae rubrathe, 6–10 Radix Astragali, and 3–5 root of Chinese trichosanthes/ND | One kind of se-rich Rehmannia glutinosa bee pollen lipid-lowering herbal tea/CN 104,336,233 A/CN | Decreasing blood lipid and blood glucose. Simple preparation. | [64] |
Wu, J.; Zhang, Y. | China | 4–6 bee pollen share, 8–10 peanuts, 6–8 Hippophae fructus powder, 5–8 Hominis placenta powder, 4–6 Astragali radix powder share, 3–5 Maydis stigma 5–8 share, wolfberry/form/ND | With Lowering Blood Pressure Multifunctional Health Product and Preparation Method Thereof./CN 106,551,357 A/CN | Blood pressure lowering. No toxicity, no side effects, short course, quick, effective, and low-cost as healthcare product. | [71] |
Inventor | Country | Ingredients/Patent Form | Patent Title/Patent Number/Patent Office | Features and Benefits | References |
---|---|---|---|---|---|
Di, D.; Pei, D. | China | 0.01–0.2 g/mL wall-broken bee pollen, 0.01–0.2 g/mL Lycium barbarum, 0.01–0.1 g/mL honey, 80 0.0005–0.003 g/mL tween, 0.0004–0.005 g/mL xanthan gum, glyceryl monostearate 0.0005–0.005, carrageenan 0.0004–0.005, sodium alginate 0.0004–0.005, citric acid 0.002–0.008 g/mL, and water/oral liquid | Oral liquid containing bee pollen and Lycium barbarum and manufacture method thereof/CN 102,742 894 A/CN | Improves immunity and fatigue resistance, and nourish the skin. | [76] |
Di, D.; Pei, D.; Liu, J. | China | Parts by wt.%: 40–50 wall-broken Fructus lycii bee pollen, 15–20 Radix codonopsis extract, 10–15 lyophilized powder of spirulina, 5–10 filler, 3–5 lubricating agent, and 1–2 essence/ND | Anti-tumor health-care food containing fructus lycii bee pollen and preparation method thereof/CN 109315739 A/CN | Improve immunity throughout human body. | [77] |
Zhang, J. | China | By wt.%: 10–95 bee pollen and 5–90 Gynostemma pentaphyllum/tablet | Method for manufacturing health care food containing gynostemma pentaphyllum and bee pollen/CN 102302107 A/CN | Increase human immunity. Decrease blood pressure, blood lipid, and sugar. Prevent tumors by inhibiting and killing cancer cells. | [78] |
Shao, S. | China | Parts by wt.: 150–180 bee pollen, 10–30 plant extract, 10–20 pupa worm intestinal extract, 10–20 modified dietary fiber, 7–15 oligosaccharide, 2–6 Lactobacillus plantarum powder, 2–6 hydroxyl isomaltulose, and 2–6 mango powder/tablets, electuary, capsules | One kind of bee pollen for improving immunity and its preparation method/CN 105,831,759 A/CN | Improves immunity. | [79] |
Liang, J. | China | bee Pollen, taizishen, longan tree parasitic, mushroom, and amino acids/ND | A Chinese medicine composition to improve immunity and preparation method thereof/CN 104257722 A/CN | Improving immune function. Quick impact and simple in preparation and execution. | [80] |
Miao, J. | China | Parts by wt.: 20–30 bee pollen, 30–50 honey, 20–30 honey lyophilized powder, 15–25 soybean lecithin powder, 10–20 spinach, 10–20 oligofructose, and 5–10 low-fat milk/capsule | Capable of improving immunity of honey pollen capsule/CN 106,666,595 A/CN | Improves immunity, high nutritional value, low cost, and simple to prepare | [81] |
Miao, J. | China | Parts by weight: 20–30 bee pollen, 30–45 honey, 20–30 honey, 20–25 Radix Astragali, 15–20 mushroom, 10–20 matrimony vine, 10–20 parts of FOS, 5–10 American ginseng, 25 ferrous lactate/capsule | A kind of honey pollen capsule for fatigue/CN 106,962,862 A/CN | Improves immunity, fatigue resistance. | [82] |
Liu, J.; Sui, Y. | China | Parts by wt.: 1–2 bee pollen, 10–20 kiwi flower, 5–10 blueberry, 50–100 honey, 2–5 honeysuckle, 2–4 Cortex eucommiae male flower, and 5–10 camellia/powder | Flower tea product and preparation method thereof/CN 112,868,847 A/CN | Enhance immunity, prevent cardiovascular diseases, antibacterial, anti-inflammatory, and hepatoprotective properties. Easy to prepare and low cost. | [83] |
Ding, H. | China | Parts by wt.: 10–40 bee pollen, 20–60 honey, 20–60 royal jelly, 1–10 bee glue, 20–30 bee placenta, 2–9 ginseng, 3–12 pseudo-ginseng, 5–18 dogwood fruit, 3–12 Rhizoma alismatis, and 5–20 Chinese wolfberry/ND | Bee-product-containing health product/CN103,238,771 A/CN | Improves immunity, expel toxins, beautify the face, anti-aging, and beneficial for the brain, kidneys, tendons, and for bone strengthening. | [84] |
Liu, J. | China | Parts by wt.: 0.01–0.015 bee pollen, 70–90 wheat flour, 5–15 wheat malt powder, 0.001–0.005 lotus root polysaccharide, 0.006–0.01 selenium-enriched yeast, 1.8–2.2 peanut sprout powder, 0.1–0.5 modifier, 0.005–0.008 corn peptide, and 0.015–0.02 white tea powder/ND | Corn peptide selenium-rich polypeptide nutrition flour/CN 104,000,080 A/CN | Improves immunocompetence. | [85] |
Bai, W. | China | By wt.%: 35–50 bee pollen (purity > 98 wt.%), 35–50 propolis powder (purity > 90 wt.%), 2–4 VC, 10–15 and auxiliary additive/capsules | Health food with vitamin C/propolis compound capsules/CN 102,132,810 A/CN | Improves immunity; regulate blood pressure; fatigue and insomnia resistance. High nutrition, high active ingredient content, low dose, low cost, and no side effects. | [86] |
Liu, Y. | China | By wt. %: 68–72 bee pollen, 8–12 honey, 18–22 Ampelopsis grossedentata, and water for balance. | Method for manufacturing healthcare tea containing bee pollen, honey, and Ampelopsis grossedentata/CN 102,224,867 A/CN | Improves immunity, decrease blood pressure, help in body weight loss, and inhibit laryngopharyngitis. | [87] |
Zhao, J. | China | By weight percent: 60–95 bee pollen, 5–30 Ginkgo biloba extract, and 0–10 starch/tablets or capsules | Method for preparing healthcare food from Ginkgo biloba extract and bee pollen/CN 101,669,640 A/CN | Improves immunity, prevent cardiovascular diseases, decrease lipid level, anti-aging, and beautifying skin. | [88] |
Chen, Wi; Chen, X. | China | By wt.: 10–40 bee pollen, 20–60 honey, 20–60 royal jelly, and 1–10 propolis/ND | Formula of bee products for improving immunity/CN 102,125,196 A/CN | Improves immunity. | [89] |
Yin, W.; Yin, Z. | China | Weight of parts: 10–60 bee pollen, 2–20 propolis, 2–20 royal jelly, 2–15 bee embryos, 2–15 been pupae, and 2–10 Panax quinquefolium/ND | Method for manufacturing honey product preparation for improving immunity/CN 102,150,770 A/CN | Improves immunity, decrease blood lipid, fatigue resistance, and anti-aging. | [90] |
Zheng, Z. | China | Parts of raw materials by weight: 1–5 bee pollen, 10–15 Salvia miltiorrhiza, 12–18 bioflavonoid, 5–10 soybean functional polysaccharide, and 2–6 Fructus lycii/ND | Natural food additive/CN 111,134,318 A/CN | Improves immunity and inhibit cancer. Decrease blood sugar and blood lipids in human body. Used as food additive due its antioxidant and bacteriostasis effects. | [91] |
Shao, S. | China | Parts by weight: 50–70 bee pollen of maize extract, 35–50 corn oligopeptide powder, 10–20 modified dietary fiber, 10–20 fruit vegetable powder, 5–20 pectin decomposer, 3–12 chrysanthemum powder, 2–10 sophora flower powder, 2–10 isomalt/ND | One kind of bee pollen for preventing and treating liver disease and enhancing the immune system and its production method/CN 104686883 A/CN | Improves immunity, and protect liver. | [75] |
Ren, X. | China | Parts by weight: 8–12 bee pollen, 4–6 medlar, 4–6 yam, 5–7 chrysanthemum, 4–6 Gordon euryale seed, 1–5 pearl barley, 2–4 red bean, 2–6 prepared Rehmannia root, 4–8 dogwood, 4–8 tuckahoe, 1–3 tree peony bark, and 0.5–1.5 oriental waterplantain rhizome/granule powder | Nutrient instant powder/CN 111671082 A/CN | Improve immunity, enhancing sleep, and anti-aging. Used as supplement. | [92] |
Zhong, H. | China | Wt. in parts: 3–5 lotus bee pollen, 3–5 linden bee honey, 1.0–1.5 protease, 1.0–1.5 wine yeast, and 88–92 purified water/ND | Method for manufacturing healthcare wine from honey and pollen/CN 102911834 A/CN | Strengthen immunity, support to the liver and kidneys, lower blood pressure, and moisturize the skin. | [93] |
Liang, Z. | China | By weight percent: 0.5–3 bee pollen, 5–18 Pseudo-ginseng, 5–12 Ginkgo biloba extract, 12–22 glucose syrup, 18–55 granulated sugar, 4–15 powdered milk, and 10–18 petal/powder | Fragrant health candy containing Panax notoginseng for resisting fatigue, anoxia, and aging, as well as reducing blood fat and sugar/CN 102058005 A/CN | Improves immunity, combats exhaustion and oxygen depletion, anti-aging, anticancer; decrease blood fat and sugar. It has nutritive value, good fragrance, and stable quality. | [94] |
Liu, J.; Yin, Y. | China | Wt. parts: 5–25 bee pollen, 25–55 royal jelly, 15–35 honey, and 15–35 wolfberry powder/ND | Composition for improving sexual function of men/CN 105433328 A/CN | Enhance immunity and improve male sexual function. | [95] |
Wang, L.; Sui, L. | China | By wt. parts: 3–9 bee pollen, 1–5 Chrysanthemum morifolium, 1–5 Shizhu Panax ginseng, 3–9 Acanthopanax sessiliflorum, 3–9 Poria cocos, 3–9 Sesamum indicum, 1–5 Semen Persicae, 1–5 Tremella fuciformis, 1–5 Auricularia auricula, 1–5 Hericium erinaceus, 2–8 Lentinus edodes, 1–5 grape seed, 0.02–0.06 lycopene, and 0.5–1.5 royal jelly/ND | Health food with antioxidation function and its manufacture method/CN 101518336 A/CN | Enhance immunity. | [96] |
Li, W.; Liu, S. | China | Fresh milk and bee pollen as main materials, adding fractions of sucrose, nourishing sugar (cerealose or glucose), and maltodextrin/milk powder | A health promotion milk powder containing bee pollen\CN 1108477 A\CN | Increased immunity and improved human physiology. | [97] |
Inventor not announced | China | By wt. parts: 10–90 Rabdosia serra and 10–90 bee pollen/tablets, granules, and capsules | Healthcare food made from Linearstripe isodon herb and bee pollen and processing method thereof/CN 102302106 A/CN | Detoxification, delaying aging, protecting the liver, and increasing human immunity. | [98] |
Inventor not announced | China | By wt. parts: 10–40 Berchemia lineata and 60–90 bee pollen/tablets, capsules, and granules | Method for manufacturing healthcare food containing Berchemia lineata and bee pollen/CN 102302105 A/CN | Increase human immunity. Good for patients with tuberculosis, diabetes, gastric ulcers, testitis, spermatorrhea, rheumatoid arthritis, lumbar genu ache, traumatic injury, and urticaria. | [99] |
Inventor not announced | China | By wt. parts: 60–95 bee pollen and 5–40 lycopene/tablets, granules, and capsules | Method for manufacturing healthcare food containing lycopene and bee pollen/CN 102302104 A/CN | Increase immunity, treat heart and cerebrovascular diseases, and good for patients with tumors, hepatitis, anemia, and diabetes. | [100] |
Li, G.; Li, H. F. | China | By wt.%: 65–85 bee pollen (purity >= 80%) and 15–35 active casein peptides (purity >= 80%)/ND | Process for manufacturing health food containing peptides and bee pollen/CN 101889667 A/CN | Delay aging, improves immunity, and resist fatigue. | [101] |
An, X. | China | 500–800 g of bee pollen and 1000–1500 g of mature honey/ND | For prevention and treatment of malignant tumor for traditional chinese medicine compound preparation and preparation method thereof/CN 106344621 A/CN | Improves gastrointestinal functions, good supplement for humans, beneficial for sleep. Strengthening chemoradiotherapy effects, improving immune function for patients with malignant tumors. | [102] |
Long, L.; Wei, Z. | China | 0.1–10% bee pollen, 0.1–20% bamboo leaf extract, and 70–99.8% carrier/feed additive | Feed additive containing bee pollen and bamboo leaf extract for improving immunologic function of livestock and poultry/CN 109170172 A/CN | Significantly improves immunity of livestock and poultry. Promotes absorption and utilization of fat-soluble vitamins and other microelements. Novel feed additive, which is safe, efficient, and environmentally friendly. | [103] |
Zhang, G. | China | Bee pollen, Vaccinium, and Rosa davurica/ND | Production of healthcare food comprising Vaccinium, Rosa davurica, and bee pollen/CN 101449824 A/CN | Enhance heart function, improve eyesight, kill bacteria, improve immunity, reduce blood fat, and combat tumors. | [104] |
Zhang, Q. | China | Bee pollen, rice flour, medlar, Zizania aquatica, apple juice, broccoli, sweet potato powder, white sugar, coix seed flour, walnut kernel, dried orange peel, honey, and olive oil/rice cake | Nutritional rice cake/CN 109170526 A/CN | Eliminating dampness and cold, enhancing immunity. | [105] |
Bai, Z. | China | Tangerine bee pollen, tangerine honey, tangerine royal jelly, fritillaria, white peony root, andRadix Angelicae Sinensis/ND | Traditional Chinese medicine with tangerine honey/CN 108450866 A/CN | Protecting liver and kidneys, remove sputum from lungs, and strengthen immunity. | [106] |
Gou, C. | China | Bee pollen, black wolfberry, maca, sheep placenta extract, royal jelly, Rhizoma polygonati, gelatin, semen coicis, walnuts, collagen, γ- linolenic, vitamin C, vitamin E/tablet | Lycium ruthenicum tablet as health product\CN 104126744 A/CN | Increase immunity, antioxidant, anti-aging, delay menopause, protect the liver, and has anti-tumor effect. | [107] |
Lin, J | China | Raw material drug by weight: 1–2 rose bee pollen, 1–2 Fructuctus schisandrae bee pollen, 1–2 honeycomb extract, 1–2 END, 1–2 Eclipta alba, 1–2 Radix paeoniae alba, and 1–2 Prunella vulgaris | A bee pollen health product and method for preparation/CN 104083464 A/CN | Significantly controls endocrine secretion, improves immunity, relieves menopausal symptoms, enhances sleep, reduces migraines, reduces blood pressure, and decreases weight. | [108] |
Inventor | Country | Ingredients/Patent Form | Title/Patent Number/Patent Office | Features and Benefits | References |
---|---|---|---|---|---|
Cao, J. | China | wt. parts: 50–80 bee pollen, 25–50 dry lotus leaves, 35–65 parched hawthorn fruit, 30–50 dried plum-leaf crab, 5–15 dried orange peel, 1–15 medicated leaven, 1–10 Rhizoma Atractylodis Macrocephalae, 1–10 Radix Codonopsis, 10–20 corn silk, 2–10 Chinese wax gourd peel, 20–30 wolfberry fruit, and 1000–3000 liquor/ND | Nelumbinis folium alcohol/CN 106701480 A/CN | Antibacterial and antiviral activity. | [128] |
Li, B.; Chen, H. | China | Parts of raw materials by weight: 7–9 bee pollen, 46–52 mushroom dregs, 28–32 malt sprouts, 16–20 soluble glass, 9–12 propolis, 85–95 bred maggots, 0.7–0.8 trypsin, 125–135 rice bran, 0.9–1.3 alpha amylase, 5–7 urea phosphate, and a sufficient amount of water/ND | Antiviral pollution-free plant nutrient solution/CN 105399564 A/CN | Antiviral activity. | [124] |
Mi, Y. | China | Parts of raw materials by weight: 5–15 g rose bee pollen, 5–15 g rape bee pollen, 5–15 g buckwheat bee pollen, 5–15 g corn bee pollen, 5–15 g lotus bee pollen, 5–15 g hundred flower bee pollen, 60–80 g honey, and 500–600 g Fenjiu honey wine/ND | Wall-broken bee pollen honey wine and preparation method thereof/CN 111454811 A/CN | Enhancing metabolism, inhibition of Helicobacter pylori growth. | [125] |
Cao, G. | China | 0.1–2% bee pollen liquid, 40–60% sorbitol, 20–40% silicon dioxide, 5–15% deionized water, 1.5–4% sodium lauryl sulfate, 0.8–1.5% sodium carboxymethyl cellulose, 0.2–0.4% titanium dioxide, 0.1–0.2% saccharin sodium, and 0.1–0.3% benzyl alcohol/toothpaste | Bee pollen healthcare toothpaste/CN 104706549 A/CN | Antibacterial and anti-inflammatory impact on teeth and gums. | [127] |
Song, H.; Wang, H. | China | 2–5% enzymolysis bee pollen, 2–5% glycerol, 0.5–1% vitamin C, 0.3–0.5% hydrolyzed fish skin collagen, 0.5–1% menthol, 1.5–2.5% surfactant, 0.1–0.5% sodium carboxymethylcellulose, 0.01–0.1% preservative, 0–1% sweetening agent, and a balance of water/mouthwash | Mouthwash for gingivitis prevention and treatment/CN 113633604 A/CN | Gingivitis prevention. | [126] |
Qiu, H. | China | 4–9 bee pollen, 40–50 Semen Maydiss, 25–30 Testa Tritici, 20–25 bean cake, 14–18 Fructus Cucurbitae moschatae, 6–15 Oleum Glycines, 7–13 yeast rich in zinc, 9–16 fishbone powder, 1–3 phosphoric acid hydrogen calcium, 0.8–1.5 threonine, 5–8 Chinese medicine extraction liquid, 1–4 salt, 3–5 Lactobacillus, 6–12 wheat meal stone, 3–5 garlicin, and 2–6 saccharin sodium/feed additive | A kind of pregnant pig feed/CN 106472843 A/CN | Antibacterial and antiviral properties. Great impact on tocolysis in midwifery. | [129] |
Inventor | Country | Components/Form | Title/Patent Number/Patent Office | Features and Benefits | References |
---|---|---|---|---|---|
Jiang, Y.; Xie, Z.; Zhang, H.G.; et al. | China | By weight parts: 20–40 bee pollen, 30–35 Hordeum vulgare powder, 25–40 lactose, and 1–3 green tea extract/ND | Healthcare Chinese medicinal composition for increasing dietary fiber, facilitating feces excretion, and removing toxins/CN 105901693 A/CN | Increased dietary fiber, thus aids constipation relief and toxin expulsion. | [135] |
Mi, Y. | China | Weight of parts: 1–5 bee pollen, 10–15 fruit, 12–18 bioflavonoid, 5–10 soybean functional polysaccharide, 2–6 medlar, 12–15 red bean, 8–12 hawthorn, 4–8 carotene, 15–20 nisin, 8–15 Cordyceps sinensis powder, 20–25 red-silk thread, and 10–15 essence/ND | Antibacterial food additive and its preparation process/CN 113424959 A/CN | Antiseptic ability, good mouthfeel and taste as food additive. | [136] |
Yin, Y.; Zhang, Y. | China | Raw materials in parts by mass: 12–22 bee pollen, 20–40 Sargassum horneri sodium alginate, 20–30 defatted soybean protein, 15–40 dextrin, 18–25 pickled red pepper, 18–20 grape seed extract, 15–18 Huanggongfjiao, 8–55 malt or wheat germ, 6–10 Radix puerariae powder, and 5–8 Salvia miltiorrhiza/ND | A type of environmentally friendly food additive and production method/CN 111955728 A/CN | Food additives, good quality of the product. | [137] |
Taihe, B.; Jizhou, C. S. | China | wt. parts: 92–95 Lini pollen, 5–8 Lini anthophorids/ND | Production method of α-linolenic acid food additive/CN 104643099 A/CN | Alpha-linolenic acid food additive with low cost. | [138] |
Liu, G.; Bai, W.; Li, N.; et al. | China | Fructus jujubae and camellia bee pollen/ND | Camellia bee pollen mixed jujube functional food and preparation method thereof/CN 105054037 A/CN | Health promotion and nutritive value. | [139] |
Fregonese, A. | France | By weight parts: 25–50 bee pollen, 50 clay, 10–25 hypromellose, 0.1–1 titanium dioxide, and copper and chlorophyllin complex/capsule | Compositions based on clay and bee pollen, method for preparing same, and nutritional and therapeutic uses thereof/WO 2012080333 A1/FR | Food supplement. | [140] |
Beu, A. I. | Romania | 5–70% beeswax, 5–95% pollen, and at least one of the following: 0.1–40% propolis tincture, 10–40% honey, 0.1–20% apilarnil, up to 95% maiden wax, 0.1–10% royal jelly, up to 20% bee venom, 15% flavoring, 30% sweetener, 60% dry fruit, 80% medicinal plant powder, and 80% seeds/tablets, pills, bon-bons, dragees, drops | Method for preparing bee product-based food supplements and confectionery products/RO 126992 B1/RO | Food supplements and confectionery Products. | [134] |
Chakhunashvili, K. G.; Chakhunashvili, D. K.; et al. | United States | wt. by percent: 33–40% bee pollen, 20–33% water, and 33–40% alcohol such as ethanol/powder | Bioactive food/US 20150093494 A1/US | Food additive for bread and other bakery products. It has nutritional value due to its content of amino acids, vitamins, and minerals. | [141] |
Gao, Z. | China | Parts by weight: 2–4 bee pollen, 6–11 lotus leaves, 3–6 Codonopsis pilosula, 8–12 purslane parts, 9–11 ethyl laurate, 1.2–2 amyl butyrate, 3–5 licorice extract, 7–9 Lycium chinense, 3–8 emulsifier, 6–10 Chinese yam, 7–8 Chinese wolfberry fruit, 8–10 bioflavonoids, 0.2–4 Stigmata maydis, and 7–9 Chinese wolfberry fruit/ND | A food additive/CN 104970367 A/CN | Food additive, good taste and nutritional value. | [142] |
Wei, X. | China | 1–5 bee pollen, 10–15 salvia, 12–18 bioflavonoids, 5–10 functional soybean polysaccharides, and 2–6 wolfberry/ND | Natural food additive/CN 104431687 A/CN | Food additive for fried food, stewing food, pastries, canned food, beverage-making process. It can enhance the body’s immunity, lower blood lipids, blood sugar, and combat cancer. | [143] |
Cheng, N.; Gao, H.; Cao, W. | China | Bee pollen and plain flour/ND | Method for manufacturing biscuits containing bee pollen/CN 102763701 A/CN | Used for preparing biscuits with high nutritive value, rich in flavonoid substances, improves immunity and cancer resistance. | [144] |
Yuan, K.; Lin, X.; Xu, D.; et al. | China | wt. by percent: 9–20% bee pollen, 20–50% okra extract, 20–40% orange peel extract, 9–20% tea polyphenol, 9–20% spiral seaweed, and 0.0003–0.0005% selenious yeast/ND | Natural food additive containing Abelmoschus esculentus extract and wenchow orange peel extract/CN 102160646 A/CN | Food additive, good antioxidant and sterilization effects, high nutritive and healthcare value, convenient use, and easy storage and transport. | [145] |
Celso de Amorim, C.; da Silva, R.; Girliane; Tania Maria; S.-S.; et al. | Portugal | Coconut monofloral bee pollen and coconut oil constituent/soft gelatinous capsules | Preparation process and formulation of soft gelatinous capsule containing coconut monofloral bee pollen and coconut oil for use as functional food/BR 102015,031440 A2/BR | Innovative formulation of a natural product of excellent quality and acceptance for dietary supplementation. | [146] |
Inventor | Country | Ingredients/Patent Form | Title/Patent Number/Patent Office | Features and Benefits | References |
---|---|---|---|---|---|
Wen, Y.; Hu, G. Wu, Z.; et al. | China | Camellia bee pollen, Apricot blossom, pea, and black rice/ND | Traditional Chinese medicine composition, traditional Chinese medicine fermented product containing same, preparation method, and applications thereof/CN 112245538 A/CN | Whitening and antioxidant cosmetics. | [150] |
Wang, W.; Wang, H. | China | Corn pollen, queen bee larva freeze-dried powder, earthworm active protein, Phyllanthus emblica extg. soln., citrus hystrix extg. soln., fungus ext. soln., and pure water/ND | The preparation method of an antioxidant and anti-aging composition/CN 112205622 A/CN | Has antioxidant and anti-aging properties. | [151] |
Yang, L.; Xu, G. Liu, A.; et al. | China | Moisturizing tinctorius bee pollen or moisturizing tinctorius inflorescence ethanol ext. or moisturizing tinctorius seed oil ext./ND | Carthamus tinctorius extract, cosmetics, and application by taking Carthamus tinctorius as active ingredient/CN 105193893 A/CN | Anti-wrinkle, whitening, sunscreen, and other skin cosmetic applications. Moisturizing and antioxidant activity. | [152] |
Xu, Z.; Yin, Y.; Dong, X.; et al. | China | wt. parts: 3 rape bee pollen ext., 2–3 cetearyl glucoside, 1–2 PEG-100 stearate, 2–6 iso-Pr myristate, 2–6 caprylic/capric triglyceride, 0.5–4 di-Me siloxane, 1–5 shea butter, 2–6 cetearyl alc., 0.5–2 acrylamide/acrylate copolymer, 0.1–0.3 Me p-hydroxybenzoate, 0.1–0.3 Pr p-hydroxybenzoate, 2–8 glycerol, 0.05–0.2 EDTA-2Na, 0.05–0.2 allantoin, 0–2 essence, 0.05–0.2 diazolidinyl urea, and water in balance/cream | Rape bee pollen extract, its preparation method, and application in anti-aging cosmetic products/CN 102188350 A/CN | Acts as anti-aging facial cream. No toxicity or other side effects. | [153] |
Markham, K. R. | New Zealand | A flavonoid or flavonoid deriv., i.e., baicalein, apigenin, luteolin, isoscutellarein, galangin, kaempferol, quercetin, pinocembrin, cinnamic acid, 3,4,5-trihydroxy cinnamic acid, 4-hydroxy cinnamic acid, 3,4-dihydroxy cinnamic acid, rutin, taxifolin, naringenin, or their derivs. From plants, pollen, bee propolis (propolis), esp. from Gingko biloba, plants of the Pinaceae family, and/or plants of the Theaceae family/cream | UV-screening composition including flavonoids or flavonoid derivatives/NZ 264108 A/NZ | Sunscreen, moisturizer, skin toner, cosmetic foundation, lipstick or cream, nail lacquer, hair shampoo, hair conditioner, hair colorant, fabric coating or protectant, laundry fabric conditioner, laundry fabric cleanser, paint stain or coating, fade-resistant ink, or dye. | [154] |
Yu, N.; Yu, Q. | China | 0.1–10 pine pollen, 0.1–10 pollen, 5–95 soy milk liq., 0.1–10 konjac flour, 0.1–10 Poria cocos powder, 1.6–20 glucomannan powder, and 3–20% xylitol powder/ND | Method for preparing composite soy milk containing micron pine pollen and konjac flour for slimming and lowering blood sugar level/CN 1785020 A/CN | Nourishes the skin. | [155] |
Wang, Z. | China | Bee pollen, an edible nanometer powder of Ganoderma spore, and banana peel/nanometer granule | A nanometer powder of Ganoderma spore/CN 1640314 A/CN | Has a beneficial skincare effect. | [156] |
Sun, J.; Cui, B.; Mao, X.; et al. | China | Bee pollen enzymic hydrolysate and nutrient soln., mask paper/ND | Preparation method of bee pollen facial mask/CN 111494294 A/CN | Used in cosmetics as a facial mask. | [157] |
Liang, B. | China | 6–7 selenium-rich Saposhnikovia divaricata, 2–3 selenium-rich Centipeda min., 3–4 Xanthium sibiricum, 0.5–1 Zingiber officinale, 3–4 Gastrodia elata, 2–3 grape seed ext. parts, 110–119 bee pollen, and 200–280 glucose syrup/ND | Selenium-rich cream candy for treating nasal concha swelling and preparation method thereof/CN 107568398 A/CN | Act as skin beautifying component. | [158] |
Shenqing, F. Z. | China | Tannin compounds from buckwheat pollen or bee pollen including 1,2,3,4,6-penta-O-galloyl-b-D-glucose and 1,2,3,4,6-penta-O-galloyl-2-O-mdigalloyl-D-glucose/ND | Preparation of tannin compounds from buckwheat pollen and application thereof/CN 107245067 A/CN | Has a good whitening effect. | [159] |
Cheng, G.; Cheng, J. | China | Ganoderma lucidum bee pollen vitamin, Ganoderma lucidum rape pollen Scutellaria baicalensis, anoderma lucidum sesame pollen natural fragrant grass anti-aging cream, Ganoderma lucidum pine pollen, Arnebia euchroma ext. anti-aging cream | Ganoderma lucidum pollen skincare anti-aging cream as cosmetic/CN 106937923 A/CN | Skincare, has good anti-radiation and anti-aging effects. | [160] |
Liang, B. | China | wt. parts: 110–119 bee pollen 6–7 Radix Stemonae, 2–3 Platycodon grandiflorum, 3–4 Xanthium sibiricum, 0.5–1 Zingiber officinale, 3–4 Gastrodia elata, 2–3 grape seed, and 200–280 glucose syrup/ND | Toffee for treating enlargement of nasal cavity and preparation method thereof/CN 106720841 A/CN | Skincare. | [161] |
Xie, J. | China | wt.: 1–5 wall-broken rose bee pollen, 1–10 aloe, 1–10 collagen, 1–5 pearl powder, 1–5 peach blossom, 1–10 Radix angelicae, 1–5 royal jelly, 1–5 lecithin, 1–5 earthworm, 0.1–1 vitamin E, 100–200 honey, and 1–8 water-soluble azone/cream | A cosmetic wrinkle-removing cream/CN 106562917 A/CN | Makes the skin delicate, increases flexibility, significantly shallows wrinkles, and makes the skin full, moisturized, and flexible. | [162] |
Ruan, D. | China | Filtrate of the fermented product of two-splitting yeast, bee pollen, silk protein, elastin, protease, eggshell membrane ext., egg white ext., propolis ext., xanthan gum, milk protein, astaxanthin, hydrolyzed silk, orange oil, pearl ext. herbal ext., and deionized water/ND | Freeze-dried essence facial mask and manufacturing process thereof/CN 111773113 A/CN | Suitable for any skin type, and used for whitening, dark spots, anti-aging, moisturizing, hydrating, sterilizing, and astringent effects. | [163] |
Mi, Y. | China | 5–15 g rape bee pollen, 5–15 g buckwheat bee pollen, 5–15 g corn bee pollen, 5–15 g rose bee pollen, 5–15 g lotus bee pollen, 5–15 g lily bee pollen, 60–80 g honey, and 500–600 g Fenjiu wine/ND | Wall-broken bee pollen honey wine and preparation method thereof/CN 111454811 A/CN | Moistened and beautified skin tissue. | [125] |
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Algethami, J.S.; El-Wahed, A.A.A.; Elashal, M.H.; Ahmed, H.R.; Elshafiey, E.H.; Omar, E.M.; Naggar, Y.A.; Algethami, A.F.; Shou, Q.; Alsharif, S.M.; et al. Bee Pollen: Clinical Trials and Patent Applications. Nutrients 2022, 14, 2858. https://doi.org/10.3390/nu14142858
Algethami JS, El-Wahed AAA, Elashal MH, Ahmed HR, Elshafiey EH, Omar EM, Naggar YA, Algethami AF, Shou Q, Alsharif SM, et al. Bee Pollen: Clinical Trials and Patent Applications. Nutrients. 2022; 14(14):2858. https://doi.org/10.3390/nu14142858
Chicago/Turabian StyleAlgethami, Jari S., Aida A. Abd El-Wahed, Mohamed H. Elashal, Hanan R. Ahmed, Esraa H. Elshafiey, Eslam M. Omar, Yahya Al Naggar, Ahmed F. Algethami, Qiyang Shou, Sultan M. Alsharif, and et al. 2022. "Bee Pollen: Clinical Trials and Patent Applications" Nutrients 14, no. 14: 2858. https://doi.org/10.3390/nu14142858