Next Article in Journal
Predictors of Renal Function Worsening in Patients with Chronic Obstructive Pulmonary Disease (COPD): A Multicenter Observational Study
Next Article in Special Issue
Urinary Tartaric Acid, a Biomarker of Wine Intake, Correlates with Lower Total and LDL Cholesterol
Previous Article in Journal
The Anti-Obesity Effects of Lemon Fermented Products in 3T3-L1 Preadipocytes and in a Rat Model with High-Calorie Diet-Induced Obesity
Previous Article in Special Issue
A Systematic Review of Carotenoids in the Management of Diabetic Retinopathy
Review

Phytosterols, Cholesterol Control, and Cardiovascular Disease

1
Nutrition Foundation of Italy, 20124 Milan, Italy
2
Department of Pharmaceutical and Pharmacological Sciences, University of Milan, 20133 Milan, Italy
3
IRCCS MultiMedica, 20099 Sesto San Giovanni, Italy
4
Department of Medicine (DIMED), University of Padova, 35128 Padova, Italy
5
FIMMG—Italian Federation of General Medicine Doctors and SIMPeSV–Italian Society of Preventive and Lifestyle Medicine, 00144 Rome, Italy
6
Department of Food Environmental and Nutritional Sciences (DeFENS), University of Milan, 20133 Milan, Italy
7
SIMG—Italian Society of General Medicine, 50142 Firenze, Italy
8
Department of Molecular Medicine, University of Padova, 35121 Padova, Italy
9
IMDEA-Food, CEI UAM+CSIC, 28049 Madrid, Spain
*
Author to whom correspondence should be addressed.
Academic Editor: Lindsay Brown
Nutrients 2021, 13(8), 2810; https://doi.org/10.3390/nu13082810
Received: 19 July 2021 / Revised: 10 August 2021 / Accepted: 13 August 2021 / Published: 16 August 2021
The use of phytosterols (or plant sterols) for the control of plasma cholesterol concentrations has recently gained traction because their efficacy is acknowledged by scientific authorities and leading guidelines. Phytosterols, marketed as supplements or functional foods, are formally classified as food in the European Union, are freely available for purchase, and are frequently used without any health professional advice; therefore, they are often self-prescribed, either inappropriately or in situations in which no significant advantage can be obtained. For this reason, a panel of experts with diverse medical and scientific backgrounds was convened by NFI—Nutrition Foundation of Italy—to critically evaluate and summarize the literature available on the topic, with the goal of providing medical doctors and all health professionals useful information to actively govern the use of phytosterols in the context of plasma cholesterol control. Some practical indications to help professionals identify subjects who will most likely benefit from the use of these products, optimizing the therapeutic outcomes, are also provided. The panel concluded that the use of phytosterols as supplements or functional foods to control Low Density Lipoprotein (LDL) cholesterol levels should be preceded by the assessment of some relevant individual characteristics: cardiovascular risk, lipid profile, correct understanding of how to use these products, and willingness to pay for the treatment. View Full-Text
Keywords: phytosterols; plant sterols; cholesterol; cardiovascular disease; supplements; functional foods phytosterols; plant sterols; cholesterol; cardiovascular disease; supplements; functional foods
Show Figures

Figure 1

MDPI and ACS Style

Poli, A.; Marangoni, F.; Corsini, A.; Manzato, E.; Marrocco, W.; Martini, D.; Medea, G.; Visioli, F. Phytosterols, Cholesterol Control, and Cardiovascular Disease. Nutrients 2021, 13, 2810. https://doi.org/10.3390/nu13082810

AMA Style

Poli A, Marangoni F, Corsini A, Manzato E, Marrocco W, Martini D, Medea G, Visioli F. Phytosterols, Cholesterol Control, and Cardiovascular Disease. Nutrients. 2021; 13(8):2810. https://doi.org/10.3390/nu13082810

Chicago/Turabian Style

Poli, Andrea, Franca Marangoni, Alberto Corsini, Enzo Manzato, Walter Marrocco, Daniela Martini, Gerardo Medea, and Francesco Visioli. 2021. "Phytosterols, Cholesterol Control, and Cardiovascular Disease" Nutrients 13, no. 8: 2810. https://doi.org/10.3390/nu13082810

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop