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Article

Growth, Tolerance, and Compliance of Infants Fed an Extensively Hydrolyzed Infant Formula with Added 2′-FL Fucosyllactose (2′-FL) Human Milk Oligosaccharide

Scientific & Medical Affairs, Abbott Nutrition, Columbus, OH 43219, USA
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Nutrients 2021, 13(1), 186; https://doi.org/10.3390/nu13010186
Received: 16 December 2020 / Revised: 29 December 2020 / Accepted: 5 January 2021 / Published: 9 January 2021
(This article belongs to the Section Clinical Nutrition)
Background: The purpose of this study was to evaluate the growth, tolerance and compliance effects of an extensively hydrolyzed formula with added 2′-FL in an intended use population of infants. Methods: A non-randomized, single-group, multicenter study was conducted. Infants (0–60 days of age) with suspected food protein allergy, persistent feeding intolerance, or presenting conditions where an extensively hydrolyzed formula (eHF) was deemed appropriate were enrolled in a 2-month feeding trial. The primary outcome was maintenance of weight for age z-score during the study. Weight, length, head circumference, formula intake, tolerance measures, clinical symptoms and questionnaires were collected. Forty-eight infants were enrolled and 36 completed the study. Results: Weight for age z-scores of infants showed a statistically significant improvement from study day 1 to study day 60 (0.32 ± 0.11, p = 0.0078). Conclusions: Overall, the results of the study demonstrate that the study formula was well tolerated, safe and supported growth in the intended population. View Full-Text
Keywords: cow milk allergy; formula intolerance; hydrolyzed formula; 2′-FL; human milk oligosaccharide cow milk allergy; formula intolerance; hydrolyzed formula; 2′-FL; human milk oligosaccharide
MDPI and ACS Style

Ramirez-Farias, C.; Baggs, G.E.; Marriage, B.J. Growth, Tolerance, and Compliance of Infants Fed an Extensively Hydrolyzed Infant Formula with Added 2′-FL Fucosyllactose (2′-FL) Human Milk Oligosaccharide. Nutrients 2021, 13, 186. https://doi.org/10.3390/nu13010186

AMA Style

Ramirez-Farias C, Baggs GE, Marriage BJ. Growth, Tolerance, and Compliance of Infants Fed an Extensively Hydrolyzed Infant Formula with Added 2′-FL Fucosyllactose (2′-FL) Human Milk Oligosaccharide. Nutrients. 2021; 13(1):186. https://doi.org/10.3390/nu13010186

Chicago/Turabian Style

Ramirez-Farias, Carlett, Geraldine E. Baggs, and Barbara J. Marriage. 2021. "Growth, Tolerance, and Compliance of Infants Fed an Extensively Hydrolyzed Infant Formula with Added 2′-FL Fucosyllactose (2′-FL) Human Milk Oligosaccharide" Nutrients 13, no. 1: 186. https://doi.org/10.3390/nu13010186

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