Next Article in Journal
Bisphenol S in Food Causes Hormonal and Obesogenic Effects Comparable to or Worse than Bisphenol A: A Literature Review
Previous Article in Journal
Iron Status and Cancer Risk in UK Biobank: A Two-Sample Mendelian Randomization Study
 
 
Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
Journals
Nutrients
Volume 12
Issue 2
10.3390/nu12020527
nutrients-logo
Submit to this Journal Review for this Journal Propose a Special Issue
► Article Menu

Article Menu

share Share announcement Help format_quote Cite question_answer Discuss in SciProfiles
first_page
settings
Order Article Reprints
Font Type:
Arial Georgia Verdana
Font Size:
Aa Aa Aa
Line Spacing:
Column Width:
Background:
Article

Postural Balance Effects Associated with 400, 4000 or 10,000 IU Vitamin D3 Daily for Three Years: A Secondary Analysis of a Randomized Clinical Trial

by
Lauren A. Burt
†,
Leigh Gabel
†,
Emma O. Billington
,
David A. Hanley
and
Steven K. Boyd
*
McCaig Institute for Bone and Joint Health, Cumming School of Medicine, University of Calgary, 3280 Hospital Drive NW, Calgary, AB T2N 4Z6, Canada
*
Author to whom correspondence should be addressed.
†
Joint first authors.
Nutrients 2020, 12(2), 527; https://doi.org/10.3390/nu12020527
Submission received: 24 January 2020 / Revised: 14 February 2020 / Accepted: 15 February 2020 / Published: 19 February 2020
Browse Figure
Review Reports Versions Notes

Abstract

Vitamin D supplementation is proposed as a fall prevention strategy, as it may improve neuromuscular function. We examined whether three years of vitamin D supplementation (400, 4000 or 10,000 IU daily) affects postural sway in older adults. Three hundred and seventy-three non-osteoporotic, vitamin D-sufficient, community-dwelling healthy adults, aged 55–70 years, were randomized to 400 (n = 124), 4000 (n = 125) or 10,000 (n = 124) IU daily vitamin D3 for three years. Sway index was assessed at baseline, 12-, 24- and 36-months using the Biosway machine. We tested participants under four conditions: eyes open or eyes closed with firm (EOFI, ECFI) or foam (EOFO, ECFO) surfaces. Secondary assessments examined sway in the anterior-posterior (AP) and medio-lateral (ML) directions. Linear mixed effects models compared sway between supplementation groups across time. Postural sway under EOFO and ECFO conditions significantly improved in all supplementation groups over time. Postural sway did not differ between supplementation groups at any time under any testing conditions in normal, AP or ML directions (p > 0.05 for all). Our findings suggest that high dose (4000 or 10,000 IU) vitamin D supplementation neither benefit nor impair balance compared with 400 IU daily in non-osteoporotic, vitamin D-sufficient, healthy older adults.
Keywords: postural sway; sway index; clinical test of sensory interaction and balance; anterior-posterior; medio-lateral; aging; supplements postural sway; sway index; clinical test of sensory interaction and balance; anterior-posterior; medio-lateral; aging; supplements

Share and Cite

MDPI and ACS Style

Burt, L.A.; Gabel, L.; Billington, E.O.; Hanley, D.A.; Boyd, S.K. Postural Balance Effects Associated with 400, 4000 or 10,000 IU Vitamin D3 Daily for Three Years: A Secondary Analysis of a Randomized Clinical Trial. Nutrients 2020, 12, 527. https://doi.org/10.3390/nu12020527

AMA Style

Burt LA, Gabel L, Billington EO, Hanley DA, Boyd SK. Postural Balance Effects Associated with 400, 4000 or 10,000 IU Vitamin D3 Daily for Three Years: A Secondary Analysis of a Randomized Clinical Trial. Nutrients. 2020; 12(2):527. https://doi.org/10.3390/nu12020527

Chicago/Turabian Style

Burt, Lauren A., Leigh Gabel, Emma O. Billington, David A. Hanley, and Steven K. Boyd. 2020. "Postural Balance Effects Associated with 400, 4000 or 10,000 IU Vitamin D3 Daily for Three Years: A Secondary Analysis of a Randomized Clinical Trial" Nutrients 12, no. 2: 527. https://doi.org/10.3390/nu12020527

APA Style

Burt, L. A., Gabel, L., Billington, E. O., Hanley, D. A., & Boyd, S. K. (2020). Postural Balance Effects Associated with 400, 4000 or 10,000 IU Vitamin D3 Daily for Three Years: A Secondary Analysis of a Randomized Clinical Trial. Nutrients, 12(2), 527. https://doi.org/10.3390/nu12020527

Note that from the first issue of 2016, this journal uses article numbers instead of page numbers. See further details here.

Article Metrics

Back to TopTop