Next Article in Journal
Complex Enterally Tube-Fed Community Patients Display Stable Tolerance, Improved Compliance and Better Achieve Energy and Protein Targets with a High-Energy, High-Protein Peptide-Based Enteral Tube Feed: Results from a Multi-Centre Pilot Study
Previous Article in Journal
Gastroesophageal Reflux Disease and Foregut Dysmotility in Children with Intestinal Failure
Open AccessReview

The Potential Role of Nutraceuticals as an Adjuvant in Breast Cancer Patients to Prevent Hair Loss Induced by Endocrine Therapy

1
Nutrafol, New York, NY 10016, USA
2
Centre for Skin Sciences, University of Bradford, Bradford BD17 7DF, UK
*
Author to whom correspondence should be addressed.
Nutrients 2020, 12(11), 3537; https://doi.org/10.3390/nu12113537
Received: 12 October 2020 / Revised: 10 November 2020 / Accepted: 16 November 2020 / Published: 18 November 2020
(This article belongs to the Section Phytochemicals and Human Health)
Nutraceuticals, natural dietary and botanical supplements offering health benefits, provide a basis for complementary and alternative medicine (CAM). Use of CAM by healthy individuals and patients with medical conditions is rapidly increasing. For the majority of breast cancer patients, treatment plans involve 5–10 yrs of endocrine therapy, but hair loss/thinning is a common side effect. Many women consider this significant, severely impacting on quality of life, even leading to non-compliance of therapy. Therefore, nutraceuticals that stimulate/maintain hair growth can be proposed. Although nutraceuticals are often available without prescription and taken at the discretion of patients, physicians can be reluctant to recommend them, even as adjuvants, since potential interactions with endocrine therapy have not been fully elucidated. It is, therefore, important to understand the modus operandi of ingredients to be confident that their use will not interfere/interact with therapy. The aim is to improve clinical/healthcare outcomes by combining specific nutraceuticals with conventional care whilst avoiding detrimental interactions. This review presents the current understanding of nutraceuticals beneficial to hair wellness and outcomes concerning efficacy/safety in breast cancer patients. We will focus on describing endocrine therapy and the role of estrogens in cancer and hair growth before evaluating the effects of natural ingredients on breast cancer and hair growth. View Full-Text
Keywords: breast cancer; estrogen receptor; hair follicle; aromatase inhibitors; tamoxifen; nutraceuticals; plant extract; endocrine therapy-induced hair loss breast cancer; estrogen receptor; hair follicle; aromatase inhibitors; tamoxifen; nutraceuticals; plant extract; endocrine therapy-induced hair loss
Show Figures

Figure 1

MDPI and ACS Style

Dell’Acqua, G.; Richards, A.; Thornton, M.J. The Potential Role of Nutraceuticals as an Adjuvant in Breast Cancer Patients to Prevent Hair Loss Induced by Endocrine Therapy. Nutrients 2020, 12, 3537. https://doi.org/10.3390/nu12113537

AMA Style

Dell’Acqua G, Richards A, Thornton MJ. The Potential Role of Nutraceuticals as an Adjuvant in Breast Cancer Patients to Prevent Hair Loss Induced by Endocrine Therapy. Nutrients. 2020; 12(11):3537. https://doi.org/10.3390/nu12113537

Chicago/Turabian Style

Dell’Acqua, Giorgio; Richards, Aleksander; Thornton, M. J. 2020. "The Potential Role of Nutraceuticals as an Adjuvant in Breast Cancer Patients to Prevent Hair Loss Induced by Endocrine Therapy" Nutrients 12, no. 11: 3537. https://doi.org/10.3390/nu12113537

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Search more from Scilit
 
Search
Back to TopTop