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Open AccessArticle

The Effects of Time Restricted Feeding on Overweight, Older Adults: A Pilot Study

Department of Aging and Geriatric Research, Institute on Aging, University of Florida, Gainesville, FL 32611, USA
Department of Clinical and Health Psychology, University of Florida, Gainesville, FL 32611, USA
Department of Medicine, Diabetes and Metabolism, University of Florida College of Medicine, Gainesville, FL 32611, USA
Author to whom correspondence should be addressed.
Nutrients 2019, 11(7), 1500;
Received: 15 April 2019 / Revised: 18 June 2019 / Accepted: 28 June 2019 / Published: 30 June 2019
(This article belongs to the Special Issue Health Effects of Intermittent Fasting: How Broad are the Benefits?)
A growing body of evidence indicates that time restricted feeding (TRF), a popular form of intermittent fasting, can activate similar biological pathways as caloric restriction, the only intervention consistently found to extend healthy lifespan in a variety of species. Thus, TRF may have the potential to also improve function in older adults. Given the challenges many individuals have in following calorie restriction regimens over long-time periods, evaluation of alternative approaches that may produce weight loss and improve function in overweight, older adults is important. Ten overweight, sedentary older adults (≥65 years) at risk for, or with mobility impairments, defined by slow gait speed (<1.0 m/s) participated in this trial. All participants received the intervention and were instructed to fast for approximately 16 h per day over the entire four-week intervention. Outcomes included changes in body weight, waist circumference, cognitive and physical function, health-related quality of life, and adverse events. Adherence levels were high (mean = 84%) based on days goal was met, and mean weight loss was 2.6 kg (p < 0.01). Since body composition was not measured in this study, it is unclear if the observed weight loss was due to loss of fat mass, muscle mass, or the combination of fat and muscle mass. There were no significant changes in other outcomes; however, there were clinically meaningful changes in walking speed and improvements in quality of life, with few reported adverse events. The findings of this pilot study suggest that time restricted feeding is an acceptable and feasible eating pattern for overweight, sedentary older adults to follow. View Full-Text
Keywords: weight loss; intermittent fasting; fat loss; sarcopenia; body composition weight loss; intermittent fasting; fat loss; sarcopenia; body composition
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Anton, S.D.; Lee, S.A.; Donahoo, W.T.; McLaren, C.; Manini, T.; Leeuwenburgh, C.; Pahor, M. The Effects of Time Restricted Feeding on Overweight, Older Adults: A Pilot Study. Nutrients 2019, 11, 1500.

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