Next Article in Journal
Mechanisms Involved in the Relationship between Low Calcium Intake and High Blood Pressure
Next Article in Special Issue
Towards a Food Pharmacy: Immunologic Modulation through Diet
Previous Article in Journal
Epimedium koreanum Extract and Its Flavonoids Reduced Atherosclerotic Risk via Suppressing Modification of Human HDL
Previous Article in Special Issue
Bases for the Adequate Development of Nutritional Recommendations for Patients with Inflammatory Bowel Disease
Open AccessReview

Inflammatory Bowel Diseases and Food Additives: To Add Fuel on the Flames!

1
INSERM unit 1073, Normandie University, UNIROUEN, 22 boulevard Gambetta, F-76183 Rouen, France
2
Institute for Research and Innovation in Biomedicine (IRIB), Normandie University, UNIROUEN, F-76183 Rouen, France
3
Department of Gastroenterology, Rouen University Hospital, 1 rue de Germont, F-76031 Rouen, France
4
Institute of Translational Medicine, University of Birmingham, Birmingham B15 2TT, UK
*
Author to whom correspondence should be addressed.
Nutrients 2019, 11(5), 1111; https://doi.org/10.3390/nu11051111
Received: 28 April 2019 / Revised: 15 May 2019 / Accepted: 16 May 2019 / Published: 18 May 2019
(This article belongs to the Special Issue Nutrition in Inflammatory Bowel Disease (IBD))
Inflammatory bowel diseases (IBDs) develop in genetically predisposed individuals in response to environmental factors. IBDs are concomitant conditions of industrialized societies, and diet is a potential culprit. Consumption of ultra-processed food has increased over the last decade in industrialized countries, and epidemiological studies have found associations between ultra-processed food consumption and chronic diseases. Further studies are now required to identify the potential culprit in ultra-processed food, such as a poor nutritional composition or the presence of food additives. In our review, we will focus on food additives, i.e., substances from packaging in contact with food, and compounds formed during production, processing, and storage. A literature search using PubMed from inception to January 2019 was performed to identify relevant studies on diet and/or food additive and their role in IBDs. Manuscripts published in English from basic science, epidemiological studies, or clinical trials were selected and reviewed. We found numerous experimental studies highlighting the key role of food additives in IBD exacerbation but epidemiological studies on food additives on IBD risk are still limited. As diet is a modifiable environmental risk factor, this may offer a scientific rationale for providing dietary advice for IBD patients. View Full-Text
Keywords: colitis; food additive; diet; emulsifiers; high salt diet; inflammatory bowel diseases colitis; food additive; diet; emulsifiers; high salt diet; inflammatory bowel diseases
Show Figures

Graphical abstract

MDPI and ACS Style

Marion-Letellier, R.; Amamou, A.; Savoye, G.; Ghosh, S. Inflammatory Bowel Diseases and Food Additives: To Add Fuel on the Flames! Nutrients 2019, 11, 1111.

Show more citation formats Show less citations formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop