Decreased Appetite is Associated with Sarcopenia-Related Outcomes in Acute Hospitalized Older Adults
by
Carliene van Dronkelaar 1,*, Michael Tieland 1, Jesse J. Aarden 2,3, Lucienne A. Reichardt 4, Rosanne van Seben 4, Marike van der Schaaf 2,3, Martin van der Esch 3,5
, Raoul H. H. Engelbert 3, Jos W. R. Twisk 6, Jos A. Bosch 7,8, Bianca M. Buurman 3,4 and on behalf of the Hospital-ADL Study Group †
Carliene van Dronkelaar 1,*, Michael Tieland 1, Jesse J. Aarden 2,3, Lucienne A. Reichardt 4, Rosanne van Seben 4, Marike van der Schaaf 2,3, Martin van der Esch 3,5, Raoul H. H. Engelbert 3, Jos W. R. Twisk 6, Jos A. Bosch 7,8, Bianca M. Buurman 3,4 and on behalf of the Hospital-ADL Study Group †
1
Faculty of Sports and Nutrition, Amsterdam University of Applied Sciences, 1067SM Amsterdam, The Netherlands
2
Department of Rehabilitation, Amsterdam Movement Sciences, Amsterdam UMC, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands
3
Faculty of Health, Amsterdam University of Applied Sciences, ACHIEVE-Center of Applied Research, 1105 BD Amsterdam, The Netherlands
4
Department of Internal Medicine, Section of Geriatric Medicine, Amsterdam Public Health Research Institute, Amsterdam UMC, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands
5
Reade, Center for Rehabilitation and Rheumatology/Amsterdam Rehabilitation Research Center, 1056 AB Amsterdam, The Netherlands
6
Department of Epidemiology and Biostatistics, Amsterdam UMC, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands
7
Department of Clinical Psychology, University of Amsterdam, 1018 WS Amsterdam, The Netherlands
8
Department of Medical Psychology, Amsterdam UMC, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands
*
Author to whom correspondence should be addressed.
†
Membership of the Hospital-ADL Study Group is provided in the acknowledgments.
Nutrients 2019, 11(4), 932; https://doi.org/10.3390/nu11040932
Received: 28 March 2019 / Revised: 18 April 2019 / Accepted: 23 April 2019 / Published: 25 April 2019
(This article belongs to the Special Issue Older Individuals' Nutrition)
Decreased appetite is one of the main risk factors of malnutrition. Little is known on how appetite changes during hospitalization and after discharge and how it relates with sarcopenia-related outcomes. We analyzed data of the Hospital-ADL study, a multicenter prospective cohort study that followed 400 acutely hospitalized older adults (≥70 year). Appetite (SNAQ), handgrip strength (Jamar), muscle mass (BIA), mobility (DEMMI), and physical performance (SPPB) were assessed within 48 h of admission, at discharge, and at one and three months post-discharge. The course of decreased appetite was analysed by Generalised Estimating Equations. Linear Mixed Model was used to analyse the associations between decreased appetite and the sarcopenia-related outcomes. Decreased appetite was reported by 51% at hospital admission, 34% at discharge, 28% one month post-discharge, and 17% three months post-discharge. Overall, decreased appetite was associated with lower muscle strength (β = −1.089, p = 0.001), lower mobility skills (β = −3.893, p < 0.001), and lower physical performance (β = −0.706, p < 0.001) but not with muscle mass (β = −0.023, p = 0.920). In conclusion, decreased appetite was highly prevalent among acute hospitalized older adults and remained prevalent, although less, after discharge. Decreased appetite was significantly associated with negative sarcopenia-related outcomes, which underlines the need for assessment and monitoring of decreased appetite during and post hospitalization.
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Keywords:
nutrition; malnutrition; post-acute care; muscle strength; muscle mass; mobility; physical performance
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited
MDPI and ACS Style
van Dronkelaar, C.; Tieland, M.; Aarden, J.J.; Reichardt, L.A.; van Seben, R.; van der Schaaf, M.; van der Esch, M.; Engelbert, R.H.H.; Twisk, J.W.R.; Bosch, J.A.; Buurman, B.M.; on behalf of the Hospital-ADL Study Group. Decreased Appetite is Associated with Sarcopenia-Related Outcomes in Acute Hospitalized Older Adults. Nutrients 2019, 11, 932.
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