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Open AccessReview

International Study of Childhood Obesity, Lifestyle and the Environment (ISCOLE): Contributions to Understanding the Global Obesity Epidemic

Pennington Biomedical Research Center, 6400 Perkins Road, Baton Rouge, LA 70808, USA
Children’s Hospital of Eastern Ontario Research Institute, Ottawa, ON K1H 8L1, Canada
Department of Food and Environmental Sciences, University of Helsinki, 00014 Helsinki, Finland
School of Health Sciences, Sansom Institute, University of South Australia, Adelaide, SA 5001, Australia
Faculdade de Desporto, University of Porto, Rua Dr. Plácido Costa, 91, 4200-450 Porto, Portugal
School of Medicine, Universidad de los Andes, Bogota 11001000, Colombia
Department for Health, University of Bath, Bath BA2 7AY, UK
Department of Kinesiology, University of Massachusetts, Amherst, MA 01003, USA
Author to whom correspondence should be addressed.
Nutrients 2019, 11(4), 848;
Received: 22 February 2019 / Revised: 9 April 2019 / Accepted: 10 April 2019 / Published: 15 April 2019
(This article belongs to the Special Issue Dietary Behavior and Physical Activity in Children and Adolescents)
The purpose of this review is to summarize the scientific contributions of the International Study of Childhood Obesity, Lifestyle and the Environment (ISCOLE) in extending our understanding about obesity in children from around the world. ISCOLE was a multi-national study of 9 to 11 year-old children from sites in 12 countries from all inhabited continents. The primary purpose was to investigate relationships between lifestyle behaviors and obesity, and the influence of higher-order characteristics such as behavioral settings, and physical, social and policy environments. ISCOLE has made several advances in scientific methodology related to the assessment of physical activity, dietary behavior, sleep and the neighborhood and school environments. Furthermore, ISCOLE has provided important evidence on (1) epidemiological transitions in obesity and related behaviors, (2) correlates of obesity and lifestyle behaviors at the individual, neighborhood and school levels, and (3) 24-h movement behaviors in relation to novel analytical techniques. A key feature of ISCOLE was the development of a platform for international training, data entry, and data quality for multi-country studies. Finally, ISCOLE represents a transparent model for future public-private research partnerships across low, middle and high-income countries. View Full-Text
Keywords: pediatric; overweight; epidemiological transition; collaboration pediatric; overweight; epidemiological transition; collaboration
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Katzmarzyk, P.T.; Chaput, J.-P.; Fogelholm, M.; Hu, G.; Maher, C.; Maia, J.; Olds, T.; Sarmiento, O.L.; Standage, M.; Tremblay, M.S.; Tudor-Locke, C. International Study of Childhood Obesity, Lifestyle and the Environment (ISCOLE): Contributions to Understanding the Global Obesity Epidemic. Nutrients 2019, 11, 848.

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