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Impact of Nutritional Changes on Nonalcoholic Fatty Liver Disease

Department of Endocrinology and Nutrition, Clínica Universidad de Navarra, 31008 Pamplona, Spain
CIBER Fisiopatología de la Obesidad y Nutrición (CIBERobn), ISCIII, 28029 Madrid, Spain
Author to whom correspondence should be addressed.
Nutrients 2019, 11(3), 677;
Received: 28 February 2019 / Revised: 15 March 2019 / Accepted: 16 March 2019 / Published: 21 March 2019
(This article belongs to the Special Issue Liver, Oxidative Stress and Metabolic Syndromes)
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Non-alcoholic fatty liver disease (NAFLD) is a major global health threat due to its growing incidence and prevalence. It is becoming the leading cause of liver disease in addition to its strong association with cardio-metabolic disease. Therefore, its prevention and treatment are of strong public interest. Therapeutic approaches emphasize lifestyle modifications including physical activity and the adoption of healthy eating habits that intend to mainly control body weight and cardio-metabolic risk factors associated with the metabolic syndrome. Lifestyle interventions may be reinforced by pharmacological treatment in advanced stages, though there is still no registered drug for the specific treatment of NAFLD. The purpose of this review is to assess the evidence available regarding the impact of dietary recommendations against NAFLD, highlighting the effect of macronutrient diet composition and dietary patterns in the management of NAFLD. View Full-Text
Keywords: NAFLD; NASH; diet; macronutrients NAFLD; NASH; diet; macronutrients

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Perdomo, C.M.; Frühbeck, G.; Escalada, J. Impact of Nutritional Changes on Nonalcoholic Fatty Liver Disease. Nutrients 2019, 11, 677.

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