Next Article in Journal
Increasing Chocolate’s Sugar Content Enhances Its Psychoactive Effects and Intake
Next Article in Special Issue
Total Dairy, Cheese and Milk Intake and Arterial Stiffness: A Systematic Review and Meta-analysis of Cross-Sectional Studies
Previous Article in Journal
Food Intake during School Lunch Is Better Explained by Objectively Measured Eating Behaviors than by Subjectively Rated Food Taste and Fullness: A Cross-Sectional Study
Review

Glycomacropeptide Bioactivity and Health: A Review Highlighting Action Mechanisms and Signaling Pathways

Department of Microbiology, Basic Science Center, Autonomous University of Aguascalientes, Aguascalientes 20131, Mexico
*
Author to whom correspondence should be addressed.
Nutrients 2019, 11(3), 598; https://doi.org/10.3390/nu11030598
Received: 1 February 2019 / Revised: 6 March 2019 / Accepted: 7 March 2019 / Published: 12 March 2019
(This article belongs to the Special Issue Dairy Products Consumption for Human Health)
Food-derived bioactive peptides are reported as beneficial and safe for human health. Glycomacropeptide (GMP) is a milk-protein-derived peptide that, in addition to its nutritional value, retains many biological properties and has therapeutic effects in several inflammatory disorders. GMP was shown under in vitro and in vivo conditions to exert a number of activities that regulate the physiology of important body systems, namely the gastrointestinal, endocrine, and immune systems. This review represents a comprehensive compilation summarizing the current knowledge and updated information on the major biological properties associated with GMP. GMP bioactivity is addressed with special attention on mechanisms of action, signaling pathways involved, and structural characteristics implicated. In addition, the results of various studies dealing with the effects of GMP on models of inflammatory diseases are reviewed and discussed. View Full-Text
Keywords: glycomacropeptide; milk-derived bioactive peptide; antibacterial; prebiotic; remineralizing; metabolism; anti-tumoral; immuno-modulatory; action mechanisms glycomacropeptide; milk-derived bioactive peptide; antibacterial; prebiotic; remineralizing; metabolism; anti-tumoral; immuno-modulatory; action mechanisms
Show Figures

Figure 1

MDPI and ACS Style

Córdova-Dávalos, L.E.; Jiménez, M.; Salinas, E. Glycomacropeptide Bioactivity and Health: A Review Highlighting Action Mechanisms and Signaling Pathways. Nutrients 2019, 11, 598. https://doi.org/10.3390/nu11030598

AMA Style

Córdova-Dávalos LE, Jiménez M, Salinas E. Glycomacropeptide Bioactivity and Health: A Review Highlighting Action Mechanisms and Signaling Pathways. Nutrients. 2019; 11(3):598. https://doi.org/10.3390/nu11030598

Chicago/Turabian Style

Córdova-Dávalos, Laura E., Mariela Jiménez, and Eva Salinas. 2019. "Glycomacropeptide Bioactivity and Health: A Review Highlighting Action Mechanisms and Signaling Pathways" Nutrients 11, no. 3: 598. https://doi.org/10.3390/nu11030598

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop