Next Article in Journal
Developmental Vitamin D Deficiency in the Rat Impairs Recognition Memory, but Has No Effect on Social Approach or Hedonia
Next Article in Special Issue
Vitamin B12 Status Upon Short-Term Intervention with a Vegan Diet—A Randomized Controlled Trial in Healthy Participants
Previous Article in Journal
Dietary and Physical Activity Behaviors in Women with Polycystic Ovary Syndrome per the New International Evidence-Based Guideline
Previous Article in Special Issue
Vegetarian Diets and Medical Expenditure in Taiwan—A Matched Cohort Study
Open AccessReview

Plant-Based Diets in the Reduction of Body Fat: Physiological Effects and Biochemical Insights

Department of Nutrition, Georgia State University, Atlanta, GA 30302, USA
*
Author to whom correspondence should be addressed.
Nutrients 2019, 11(11), 2712; https://doi.org/10.3390/nu11112712
Received: 2 October 2019 / Revised: 30 October 2019 / Accepted: 5 November 2019 / Published: 8 November 2019
(This article belongs to the Special Issue Vegetarian, Vegan Diets and Human Health)
Obesity affects over one-third of Americans and increases the risk of cardiovascular disease and type II diabetes. Interventional trials have consistently demonstrated that consumption of plant-based diets reduces body fat in overweight and obese subjects, even when controlling for energy intake. Nonetheless, the mechanisms underlying this effect have not been well-defined. This review discusses six major dietary mechanisms that may lead to reduced body fat. These include (1) reduced caloric density, (2) improved gut microbiota symbiosis, (3) increased insulin sensitivity, (4) reduced trimethylamine-N-oxide (TMAO), (5) activation of peroxisome proliferator-activated receptors (PPARs), and (6) over-expression of mitochondrial uncoupling proteins. Collectively, these factors improve satiety and increase energy expenditure leading to reduced body weight.
Keywords: diet; nutrition; vegetarian; vegan; microbiome; TMAO; PPAR; weight loss; obesity diet; nutrition; vegetarian; vegan; microbiome; TMAO; PPAR; weight loss; obesity
MDPI and ACS Style

Najjar, R.S.; Feresin, R.G. Plant-Based Diets in the Reduction of Body Fat: Physiological Effects and Biochemical Insights. Nutrients 2019, 11, 2712.

Show more citation formats Show less citations formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop