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Evidence on the Health Benefits of Supplemental Propolis

Faculty of Medical Health Science, The University of Auckland, Auckland 1010, New Zealand
Nutrients 2019, 11(11), 2705;
Received: 15 July 2019 / Revised: 17 October 2019 / Accepted: 30 October 2019 / Published: 8 November 2019
(This article belongs to the Special Issue Dietary Polyphenols and Cardiometabolic Diseases)
Propolis is a honey-related product with reported health benefits such as improved immunity, lowered blood pressure, treated allergies and skin conditions. A literature review and narrative synthesis were conducted to investigate the evidence on the reported health benefits and future direction of propolis products. Using a predefined search strategy we searched Medline (OvidSP), Embase and Central for quantitative and qualitative studies (1990–2018). Citation, reference, hand searches and expert consultation were also undertaken. Studies of randomised control trials and observational data on humans with health-related outcomes were included. Collected data were entered into NVivo software (Version 12, QRS International) and analysed using a thematic framework and a narrative synthesis of emergent themes. A total of 63 publications were discussed. The majority were cell-based and animal studies, with a few key human trials conducted. There is significant promise for propolis as an effective antioxidant and anti-inflammatory agent with particular promise in cardiometabolic health. View Full-Text
Keywords: bioactives; nutrition; cardiovascular; stroke bioactives; nutrition; cardiovascular; stroke
MDPI and ACS Style

Braakhuis, A. Evidence on the Health Benefits of Supplemental Propolis. Nutrients 2019, 11, 2705.

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  • Externally hosted supplementary file 1
    Doi: 10.5281/zenodo.3334965
    Description: Supplementary Data S1 Figure 1: PRISMA search chart Supplementary Data S1 Table 1 Search strategy
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