Next Article in Journal
Dietary Carotenoids Intake and the Risk of Gastric Cancer: A Case—Control Study in Korea
Next Article in Special Issue
Vegetable Diversity, Injurious Falls, and Fracture Risk in Older Women: A Prospective Cohort Study
Previous Article in Journal
Volatile Terpenes and Brain Function: Investigation of the Cognitive and Mood Effects of Mentha × Piperita L. Essential Oil with In Vitro Properties Relevant to Central Nervous System Function
Previous Article in Special Issue
Long-Term Dietary Intake of Chia Seed Is Associated with Increased Bone Mineral Content and Improved Hepatic and Intestinal Morphology in Sprague-Dawley Rats

Osteoarthritis and the Mediterranean Diet: A Systematic Review

Department of Rheumatology, Bellvitge University Hospital-IDIBELL, L’Hospitalet de Llobregat, 08907 Barcelona, Spain
School of Health and Sport Sciences (EUSES), University of Girona, 17190 Salt, Spain
Blanquerna Faculty of Psychology, Education Sciences and Sport (FPCEE), Universitat Ramon Llull, 08022 Barcelona, Spain
CIBER Fisiopatología de la Obesidad y Nutrición (CIBERobn), Instituto de Salud Carlos III (ISCIII), 28029 Madrid, Spain
Research Institute of Biomedical and Health Sciences IUIBS, University of Las Palmas de Gran Canaria, 35001 Las Palmas de Gran Canaria, Spain
Nutrition Research Foundation, University of Barcelona Science Park, 08028 Barcelona, Spain
Author to whom correspondence should be addressed.
Nutrients 2018, 10(8), 1030;
Received: 3 July 2018 / Revised: 31 July 2018 / Accepted: 1 August 2018 / Published: 7 August 2018
(This article belongs to the Special Issue Dietary Intake and Musculoskeletal Health)
Osteoarthritis (OA) affects 240 million people globally. Few studies have examined the links between osteoarthritis and the Mediterranean diet (MD). The aim of this paper was to systematically review and analyze the epidemiological evidence in humans on the MD and its association with OA. A systematic search of EMBASE identified three studies that explored the association between MD and OA. Two of them were cross-sectional and the third one was a 16-week randomized clinical trial. Prisma declaration was followed to carry out this review. These studies described a positive association between a higher adherence to a MD and the quality of life of participants suffering OA. The prevalence of OA was lower in participants with a higher adherence to a Mediterranean diet. Biomarkers of inflammation and cartilage degradation related to OA were also analyzed and significant differences were detected only for IL1-α, which decreased in the MD group. Exploring the relationship between MD and OA is complex, moreover, the limited evidence and methodological differences in such studies makes it difficult to compare results. In conclusion, the three studies included in this systematic review demonstrated some relation between osteoarthritis and a Mediterranean diet. However, prospective and longer interventions are required to evaluate the long-term efficacy of the Mediterranean diet to improve symptomatology and preventing osteoarthritis. View Full-Text
Keywords: Mediterranean diet; osteoarthritis; systematic review Mediterranean diet; osteoarthritis; systematic review
Show Figures

Figure 1

MDPI and ACS Style

Morales-Ivorra, I.; Romera-Baures, M.; Roman-Viñas, B.; Serra-Majem, L. Osteoarthritis and the Mediterranean Diet: A Systematic Review. Nutrients 2018, 10, 1030.

AMA Style

Morales-Ivorra I, Romera-Baures M, Roman-Viñas B, Serra-Majem L. Osteoarthritis and the Mediterranean Diet: A Systematic Review. Nutrients. 2018; 10(8):1030.

Chicago/Turabian Style

Morales-Ivorra, Isabel, Montserrat Romera-Baures, Blanca Roman-Viñas, and Lluis Serra-Majem. 2018. "Osteoarthritis and the Mediterranean Diet: A Systematic Review" Nutrients 10, no. 8: 1030.

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

Back to TopTop