Next Article in Journal
Regulation of Muscle Glycogen Metabolism during Exercise: Implications for Endurance Performance and Training Adaptations
Next Article in Special Issue
Higher Dietary Magnesium Intake and Higher Magnesium Status Are Associated with Lower Prevalence of Coronary Heart Disease in Patients with Type 2 Diabetes
Previous Article in Journal
Use of Table Sugar and Artificial Sweeteners in Brazil: National Dietary Survey 2008–2009
Previous Article in Special Issue
Dietary Magnesium and Cardiovascular Disease: A Review with Emphasis in Epidemiological Studies
Open AccessArticle

Dietary Magnesium Intake and Hyperuricemia among US Adults

by Yiying Zhang 1,2 and Hongbin Qiu 1,2,*
Department of Epidemiology, School of Public Health, Harbin Medical University, Harbin 150081, China
School of Public Health, Jiamusi University, Jiamusi 154007, China
Author to whom correspondence should be addressed.
Nutrients 2018, 10(3), 296;
Received: 23 January 2018 / Revised: 24 February 2018 / Accepted: 27 February 2018 / Published: 2 March 2018
(This article belongs to the Special Issue Magnesium Intake and Human Health)
To assess the association between dietary magnesium intake and hyperuricemia in United States (US) adults, we extracted 26,796 US adults aged 20–85 years from the National Health and Nutrition Examination Survey (NHANES) in 2001–2014. All dietary intake was measured through 24 h dietary recall method. Multivariable logistic regression analysis was performed to investigate the association between magnesium intake and hyperuricemia after adjusting for several important confounding variables. When compared to the lowest quintile (Q1), for male, adjusted odds ratios (ORs) of hyperuricemia in the second quintile (Q2) to the fifth quintile (Q5) of the magnesium intake were 0.83 (95% CI: 0.72–0.95), 0.74 (0.64–0.85), 0.78 (0.67–0.90), and 0.70 (0.58–0.84, p for trend = 0.0003), respectively. For female, OR was 0.75 (0.62–0.90) in the fourth quintile (Q4) (p for trend = 0.0242). As compared to Q4 of magnesium intake (contains recommended amount), the relative odds of hyperuricemia were increased by 1.29 times in Q1 (OR = 1.29, 1.11–1.50) in male. The ORs were 1.33 (1.11–1.61) in Q1, 1.27 (1.07–1.50) in Q2 in female. Our results indicated that increased magnesium intake was associated with decreased hyperuricemia risk. It also indicated the importance of recommended dietary allowance (RDA) of magnesium and the potential function of magnesium intake in the prevention of hyperuricemia. View Full-Text
Keywords: hyperuricemia; magnesium; NHANES; cross-sectional study hyperuricemia; magnesium; NHANES; cross-sectional study
MDPI and ACS Style

Zhang, Y.; Qiu, H. Dietary Magnesium Intake and Hyperuricemia among US Adults. Nutrients 2018, 10, 296.

Show more citation formats Show less citations formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

Back to TopTop