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Article

Association between Fasting Glucose Concentration, Lipid Profile and 25(OH)D Status in Children Aged 9–11

1
Department of Laboratory Medicine, Nicolaus Copernicus University, Collegium Medicum, 85094 Bydgoszcz, Poland
2
Outpatient Clinic, “Esculap”, 88140 Gniewkowo, Poland
*
Author to whom correspondence should be addressed.
Nutrients 2018, 10(10), 1359; https://doi.org/10.3390/nu10101359
Received: 18 August 2018 / Revised: 12 September 2018 / Accepted: 19 September 2018 / Published: 22 September 2018
(This article belongs to the Special Issue Nutrition and Chronic Conditions)
Background: The aim of this study was to assess the relationship between vitamin D status and the prevalence of dyslipidemia and impaired fasting glucose (IFG) in children. Methods and Summary: 284 children (150 boys and 134 girls) aged 9–11 were included in the study. Children with deficient 25(OH)D (25-hydroxycholecalciferol) levels ≤20 ng/mL (50 nmol/L) were characterized by a more frequent occurrence of impaired fasting glucose (IFG) (Odd ratios (OR) = 1.966, 95% confidence interval (CI): 1.055–3.663; p = 0.033) when compared to children with 25(OH)D >20 ng/mL. Serum 25(OH)D with concentration lower by 1 ng/mL (2.5 nmol/L) was linked to higher fasting glucose (by 0.25 mg/dL, 0.013 mmol/L; p = 0.017), higher total cholesterol (TC) by almost 1 mg/dL (0.96 mg/dL, 0.25 mmol/L; p = 0.006) and higher high-density lipoprotein cholesterol (HDL-C) (by 0.57 mg/dL, 0.015 mmol/L; p < 0.001). Conclusion: 25(OH)D deficiency may negatively affect fasting glucose and total cholesterol concentration in children aged 9–11. Vitamin D-deficient children are twice as likely to develop prediabetes as reflected by impaired fasting glucose when compared to those with a 25(OH)D level above 20 ng/mL (50 nmol/L). View Full-Text
Keywords: 25(OH)D deficiency; children; impaired fasting glucose; hypercholesterolemia 25(OH)D deficiency; children; impaired fasting glucose; hypercholesterolemia
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MDPI and ACS Style

Szternel, L.; Krintus, M.; Bergmann, K.; Derezinski, T.; Sypniewska, G. Association between Fasting Glucose Concentration, Lipid Profile and 25(OH)D Status in Children Aged 9–11. Nutrients 2018, 10, 1359. https://doi.org/10.3390/nu10101359

AMA Style

Szternel L, Krintus M, Bergmann K, Derezinski T, Sypniewska G. Association between Fasting Glucose Concentration, Lipid Profile and 25(OH)D Status in Children Aged 9–11. Nutrients. 2018; 10(10):1359. https://doi.org/10.3390/nu10101359

Chicago/Turabian Style

Szternel, Lukasz, Magdalena Krintus, Katarzyna Bergmann, Tadeusz Derezinski, and Grazyna Sypniewska. 2018. "Association between Fasting Glucose Concentration, Lipid Profile and 25(OH)D Status in Children Aged 9–11" Nutrients 10, no. 10: 1359. https://doi.org/10.3390/nu10101359

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