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Article

The Clinical Utility of ABO and RHD Systems as Potential Indicators of Health Status, a Preliminary Study in Greek Population

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Department of Biomedical Sciences, International Hellenic University, 57001 Thessaloniki, Greece
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Lab of Computing and Medical Informatics, Medical School, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece
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Department of Statistics and Insurance Science, University of Piraeus, 18534 Piraeus, Greece
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Blood Bank Section, Naousa General Hospital, 59200 Naousa, Greece
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Laboratory of Biopathology, Hippokratio General Hospital, 54642 Thessaloniki, Greece
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Faculty of Health Sciences, School of Dentistry, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece
*
Author to whom correspondence should be addressed.
Academic Editor: Anna Capasso
Clin. Pract. 2022, 12(3), 406-418; https://doi.org/10.3390/clinpract12030045
Received: 18 March 2022 / Revised: 16 May 2022 / Accepted: 27 May 2022 / Published: 7 June 2022
Objective: The objective of this study is to further highlight the differences between different ABO blood groups and Rhesus types with health biomarkers. Methods: In total 150 active healthy blood donors participated in our study comprising of 80 males from 19–61 years and 70 females aged from 21 to 64. Participants carrying blood group A were 55 individuals, blood group B 32, blood group O 51, and blood group AB 12, RHD+ 132, and RHD- 18. All the volunteer regular blood donors were selected recognizing them as a healthy population excluding drug and supplements intake. Their blood samples were analyzed just before blood donation for biochemical, hematological, and antioxidant markers. Statistical computations were performed using the SPSS tool, specifically, the one-way ANOVA test, Chi-square statistics, and logistic regression were used as statistical models. Results: O blood donors presented better iron absorption and the worst lipid profile. Indeed, a significant trend of high atheromatic index values revealed an increased risk for hyperlipidemia, in contrast with blood group A presenting a better lipid profile with lower atheromatic index values. There was also a gender related association for blood group A compared with O that was further highlighted using binary logistic regression. Conclusion: In this study, a significant difference was observed among the ABO blood groups in several of the examined biochemical and hematological biomarkers. O blood group appeared different behavior in comparison to all the tested blood groups and furthermore the RHD-group presented a better lipid profile in comparison to the RHD+ group. In order to obtain a more comprehensive view of the correlation between the ABO blood group and biochemical markers, further studies are required. View Full-Text
Keywords: ABO blood system; Rhesus type; health biomarkers; lipid profile; atheromatic index; total antioxidant status ABO blood system; Rhesus type; health biomarkers; lipid profile; atheromatic index; total antioxidant status
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MDPI and ACS Style

Lymperaki, E.; Stalika, E.; Tzavelas, G.; Tormpantoni, E.; Samara, D.; Vagdatli, E.; Tsamesidis, I. The Clinical Utility of ABO and RHD Systems as Potential Indicators of Health Status, a Preliminary Study in Greek Population. Clin. Pract. 2022, 12, 406-418. https://doi.org/10.3390/clinpract12030045

AMA Style

Lymperaki E, Stalika E, Tzavelas G, Tormpantoni E, Samara D, Vagdatli E, Tsamesidis I. The Clinical Utility of ABO and RHD Systems as Potential Indicators of Health Status, a Preliminary Study in Greek Population. Clinics and Practice. 2022; 12(3):406-418. https://doi.org/10.3390/clinpract12030045

Chicago/Turabian Style

Lymperaki, Evgenia, Evangelia Stalika, George Tzavelas, Efthymia Tormpantoni, Diana Samara, Eleni Vagdatli, and Ioannis Tsamesidis. 2022. "The Clinical Utility of ABO and RHD Systems as Potential Indicators of Health Status, a Preliminary Study in Greek Population" Clinics and Practice 12, no. 3: 406-418. https://doi.org/10.3390/clinpract12030045

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