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Article

Application of Negative Pressure Therapy on Skin Grafts after Soft-Tissue Reconstruction: A Prospective Observational Study

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Department of Surgery, King Faisal Specialist Hospital and Research Centre, P.O. Box 40047, Jeddah 21499, Saudi Arabia
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Intensive Care Service Department, King Fahad Armed Force Hospital, P.O. Box 9862, Jeddah 21159, Saudi Arabia
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General Surgery Department, Security Forces Hospital, P.O. Box 14799, Mecca 21955, Saudi Arabia
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General Surgery Department, International Medical Center, P.O. Box 2172, Jeddah 21451, Saudi Arabia
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General Pediatric Department, King Abdulaziz Medical City, P.O. Box 9515, Jeddah 21423, Saudi Arabia
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General Surgery Department, Heraa General Hospital, Mecca 24227, Saudi Arabia
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Plastic Surgery and Burn Unit, Dr. Soliman Fakeeh Hospital, P.O. Box 2537, Jeddah 21461, Saudi Arabia
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Clinical Sciences Department, Fakeeh College for Medical Sciences, P.O. Box 2537, Jeddah 21461, Saudi Arabia
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Author to whom correspondence should be addressed.
Academic Editor: Anna Capasso
Clin. Pract. 2022, 12(3), 396-405; https://doi.org/10.3390/clinpract12030044
Received: 30 April 2022 / Revised: 25 May 2022 / Accepted: 29 May 2022 / Published: 7 June 2022
A split-thickness skin graft (STSG) is one of the main tools used in the reconstruction of skin defects. Negative-pressure wound therapy (NPWT) has been widely used as adjunct therapy for wound healing for decades. Few studies have conducted the outcomes of NPWT use as a postoperative dressing for STSGs. This study aimed to compare the outcomes of the application of NPWT versus conventional dressing on STSGs after soft-tissue reconstruction. A prospective observational study was performed at the King Abdullah Medical City. A total of 18 patients with STSGs for acute or chronic skin defects were recruited. Patients from the two groups—10 patients in the NPWT group and 8 in the No-NPWT group—were postoperatively evaluated for three weeks. Assessment included the STSG take rate, wound healing, pain, infection, hematoma formation, and the need to re-graft the same recipient area. Our data demonstrated a higher mean skin graft take rate in the second and third weeks of the No-NPWT group compared to the NPWT group, but it was not statistically significant (p > 0.05). No significant differences between the two groups in terms of wound healing, pain, infection, hematoma formation, and the need to re-graft (p > 0.05) were found. Our study showed that the conventional dressing of STSGs is not inferior to NPWT. In addition, conventional dressing was shown to be easier to use and less expensive to apply, as well as having a higher skin graft take rate and lower infection rate. View Full-Text
Keywords: split-thickness skin grafts; dressings; negative-pressure wound therapy; vacuum-assisted closure; wound healing split-thickness skin grafts; dressings; negative-pressure wound therapy; vacuum-assisted closure; wound healing
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MDPI and ACS Style

Mandili, A.; Aljubairy, A.; Alsharif, B.; Patwa, W.; Alotibey, K.; Basha, S.; Alharbi, Z. Application of Negative Pressure Therapy on Skin Grafts after Soft-Tissue Reconstruction: A Prospective Observational Study. Clin. Pract. 2022, 12, 396-405. https://doi.org/10.3390/clinpract12030044

AMA Style

Mandili A, Aljubairy A, Alsharif B, Patwa W, Alotibey K, Basha S, Alharbi Z. Application of Negative Pressure Therapy on Skin Grafts after Soft-Tissue Reconstruction: A Prospective Observational Study. Clinics and Practice. 2022; 12(3):396-405. https://doi.org/10.3390/clinpract12030044

Chicago/Turabian Style

Mandili, Aeshah, Abdullah Aljubairy, Bayan Alsharif, Wala Patwa, Khlood Alotibey, Sara Basha, and Ziyad Alharbi. 2022. "Application of Negative Pressure Therapy on Skin Grafts after Soft-Tissue Reconstruction: A Prospective Observational Study" Clinics and Practice 12, no. 3: 396-405. https://doi.org/10.3390/clinpract12030044

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