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Pediatric Reports
Volume 3
Issue 1
10.4081/pr.2011.e6
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Article

Current Evidence of Antifungal Prophylaxis and Therapy in Pediatric Patients

by
Mareva Giacchino
1,*,
Giuseppe Maria Milano
2,
Francesca Carraro
1,
Stefania Bezzio
1,
Anna Pegoraro
3,
Franco Aversa
2 and
Simone Cesaro
3
1
Pediatric Hematology Oncology and Bone Marrow Unit, Ospedale Infantile Regina Margherita, Torino, Italy
2
Pediatric Oncohematology and Bone Marrow Unit, Azienda Ospedaliera di Perugia, Italy
3
Pediatric Hematology Oncology, Azienda Ospedaliera Universitaria Integrata, Verona, Italy
*
Author to whom correspondence should be addressed.
Pediatr. Rep. 2011, 3(1), e6; https://doi.org/10.4081/pr.2011.e6
Submission received: 13 December 2010 / Revised: 3 March 2011 / Accepted: 10 March 2011 / Published: 10 March 2011

Abstract

Invasive fungal infections (IFI) are an important complication in pediatric haematological and oncological patients who undergo intensive chemotherapy for leukemia, solid tumour at advanced stage or relapsed, and hematopoietic stem cell transplantation. The incidence of IFI is lower than bacterial infection but mortality rate remains high. This review is designed to help paediatric oncologists in choosing the appropriate anti-fungal strategy and agents for prophylaxis, empirical, pre-emptive and specific therapy on the basis of published evidence.
Keywords: fungal infection; pediatric malignancy fungal infection; pediatric malignancy

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MDPI and ACS Style

Giacchino, M.; Milano, G.M.; Carraro, F.; Bezzio, S.; Pegoraro, A.; Aversa, F.; Cesaro, S. Current Evidence of Antifungal Prophylaxis and Therapy in Pediatric Patients. Pediatr. Rep. 2011, 3, e6. https://doi.org/10.4081/pr.2011.e6

AMA Style

Giacchino M, Milano GM, Carraro F, Bezzio S, Pegoraro A, Aversa F, Cesaro S. Current Evidence of Antifungal Prophylaxis and Therapy in Pediatric Patients. Pediatric Reports. 2011; 3(1):e6. https://doi.org/10.4081/pr.2011.e6

Chicago/Turabian Style

Giacchino, Mareva, Giuseppe Maria Milano, Francesca Carraro, Stefania Bezzio, Anna Pegoraro, Franco Aversa, and Simone Cesaro. 2011. "Current Evidence of Antifungal Prophylaxis and Therapy in Pediatric Patients" Pediatric Reports 3, no. 1: e6. https://doi.org/10.4081/pr.2011.e6

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