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Pediatric Reports
Volume 3
Issue 1
10.4081/pr.2011.e2
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Brief Report

Association of Environment and Place of Birth with Asthma in Chinese Immigrant Children

by
Doug Brugge
1,*,
Mark Woodin
2,
Madhuri Indaram
3,
Dora Hui
4 and
Michelle Pallela
1
1
Tufts University School of Medicine, Department of Public Health and Family Medicine, Boston, MA, USA
2
Tufts University School of Engineering, Department of Civil and Environmental Engineering, Medford, MA, USA
3
Tufts University School of Arts and Sciences, Medford, MA, USA
4
Wellesley College, Wellesley, MA, USA
*
Author to whom correspondence should be addressed.
Pediatr. Rep. 2011, 3(1), e2; https://doi.org/10.4081/pr.2011.e2
Submission received: 10 January 2011 / Revised: 1 March 2011 / Accepted: 2 March 2011 / Published: 11 March 2011

Abstract

Despite the advances in perinatal and neonatal care and use of newer potent antibiotics, the incidence of neonatal sepsis remains high and the outcome is still severe. For years, investigators have sought a test or panel of tests able to identify septic neonates accurately and rapidly in order to obtain an early diagnosis and develop a specific effective treatment for a successful outcome. In addition to the standard procedures (blood, CSF, and urine cultures, chest x-ray), such panels have included a combination of total and differential cell counts, total immature neutrophil counts, immature to total neutrophil ratio, platelet counts, and levels of acute-phase reactants and cytokines. Furthermore, the science of proteomics and genomics has been applied to the search for biomarkers, production of protein profiles and genetic polymorphisms that can rapidly help the prediction, early diagnosis, and treatment of human diseases, but, for now, data are as yet insufficient to confirm their validity.
Keywords: asthma; hygiene hypothesis; sanitation; effect modification; place of birth asthma; hygiene hypothesis; sanitation; effect modification; place of birth

Share and Cite

MDPI and ACS Style

Brugge, D.; Woodin, M.; Indaram, M.; Hui, D.; Pallela, M. Association of Environment and Place of Birth with Asthma in Chinese Immigrant Children. Pediatr. Rep. 2011, 3, e2. https://doi.org/10.4081/pr.2011.e2

AMA Style

Brugge D, Woodin M, Indaram M, Hui D, Pallela M. Association of Environment and Place of Birth with Asthma in Chinese Immigrant Children. Pediatric Reports. 2011; 3(1):e2. https://doi.org/10.4081/pr.2011.e2

Chicago/Turabian Style

Brugge, Doug, Mark Woodin, Madhuri Indaram, Dora Hui, and Michelle Pallela. 2011. "Association of Environment and Place of Birth with Asthma in Chinese Immigrant Children" Pediatric Reports 3, no. 1: e2. https://doi.org/10.4081/pr.2011.e2

APA Style

Brugge, D., Woodin, M., Indaram, M., Hui, D., & Pallela, M. (2011). Association of Environment and Place of Birth with Asthma in Chinese Immigrant Children. Pediatric Reports, 3(1), e2. https://doi.org/10.4081/pr.2011.e2

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