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Neurology International
Volume 15
Issue 2
10.3390/neurolint15020035
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Case Report

Post-Polio Syndrome Revisited

by
Michael Punsoni
,
Nelli S. Lakis
,
Michelle Mellion
and
Suzanne M. de la Monte
*
Division of Neuropathology, Departments of Pathology and Laboratory Medicine, Neurology, and Neurosurgery, Rhode Island Hospital, Alpert Medical School of Brown University, Providence, RI 02903, USA
*
Author to whom correspondence should be addressed.
Neurol. Int. 2023, 15(2), 569-579; https://doi.org/10.3390/neurolint15020035
Submission received: 16 February 2023 / Revised: 11 March 2023 / Accepted: 27 March 2023 / Published: 13 April 2023
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Abstract

Post-polio syndrome (PPS) is characterized by recrudescence or worsening of motor neuron disease symptoms decades after recovery from acute paralytic poliovirus infection, i.e., poliomyelitis. PPS afflicts between 25% and 40% of poliomyelitis survivors and mimics motor neuron diseases (MNDs), such as amyotrophic lateral sclerosis (ALS), due to its selective impairment, degeneration, or death of motor neurons in the brainstem and spinal cord. Herein, we report a case of PPS in a 68-year-old man with a remote history of bulbar and cervical cord involvement by poliomyelitis, review the relevant literature, and contrast the salient histopathologic features that distinguish our case of PPS from ALS.
Keywords: post-polio syndrome; motor neuron disease; amyotrophic lateral sclerosis post-polio syndrome; motor neuron disease; amyotrophic lateral sclerosis

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MDPI and ACS Style

Punsoni, M.; Lakis, N.S.; Mellion, M.; de la Monte, S.M. Post-Polio Syndrome Revisited. Neurol. Int. 2023, 15, 569-579. https://doi.org/10.3390/neurolint15020035

AMA Style

Punsoni M, Lakis NS, Mellion M, de la Monte SM. Post-Polio Syndrome Revisited. Neurology International. 2023; 15(2):569-579. https://doi.org/10.3390/neurolint15020035

Chicago/Turabian Style

Punsoni, Michael, Nelli S. Lakis, Michelle Mellion, and Suzanne M. de la Monte. 2023. "Post-Polio Syndrome Revisited" Neurology International 15, no. 2: 569-579. https://doi.org/10.3390/neurolint15020035

APA Style

Punsoni, M., Lakis, N. S., Mellion, M., & de la Monte, S. M. (2023). Post-Polio Syndrome Revisited. Neurology International, 15(2), 569-579. https://doi.org/10.3390/neurolint15020035

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