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Review

Dengue: A Minireview

1
Medical Research Unit, School of Medicine, Universitas Syiah Kuala, Banda Aceh, Aceh 23111, Indonesia
2
Department of Microbiology, School of Medicine, Universitas Syiah Kuala, Banda Aceh, Aceh 23111, Indonesia
3
Tropical Disease Centre, School of Medicine, Universitas Syiah Kuala, Banda Aceh, Aceh 23111, Indonesia
4
School of Biomedical Sciences, University of Western Australia, Nedlands, WA 6009, Australia
5
Eijkman Institute for Molecular Biology, Jakarta 10430, Indonesia
*
Authors to whom correspondence should be addressed.
Viruses 2020, 12(8), 829; https://doi.org/10.3390/v12080829
Submission received: 9 March 2020 / Revised: 14 June 2020 / Accepted: 23 June 2020 / Published: 30 July 2020
(This article belongs to the Special Issue 7th Pan-American Dengue Research Network Meeting: Lima 2020)

Abstract

Dengue, caused by infection of any of four dengue virus serotypes (DENV-1 to DENV-4), is a mosquito-borne disease of major public health concern associated with significant morbidity, mortality, and economic cost, particularly in developing countries. Dengue incidence has increased 30-fold in the last 50 years and over 50% of the world’s population, in more than 100 countries, live in areas at risk of DENV infection. We reviews DENV biology, epidemiology, transmission dynamics including circulating serotypes and genotypes, the immune response, the pathogenesis of the disease as well as updated diagnostic methods, treatments, vector control and vaccine developments.
Keywords: dengue; epidemiology; pathogenesis; diagnosis; treatment; disease control dengue; epidemiology; pathogenesis; diagnosis; treatment; disease control

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MDPI and ACS Style

Harapan, H.; Michie, A.; Sasmono, R.T.; Imrie, A. Dengue: A Minireview. Viruses 2020, 12, 829. https://doi.org/10.3390/v12080829

AMA Style

Harapan H, Michie A, Sasmono RT, Imrie A. Dengue: A Minireview. Viruses. 2020; 12(8):829. https://doi.org/10.3390/v12080829

Chicago/Turabian Style

Harapan, Harapan, Alice Michie, R. Tedjo Sasmono, and Allison Imrie. 2020. "Dengue: A Minireview" Viruses 12, no. 8: 829. https://doi.org/10.3390/v12080829

APA Style

Harapan, H., Michie, A., Sasmono, R. T., & Imrie, A. (2020). Dengue: A Minireview. Viruses, 12(8), 829. https://doi.org/10.3390/v12080829

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